What’s Inside Every Chew
Clear ingredient information, organised by the six pillars of canine wellbeing.
At a Glance
At a GlanceA clear, transparent look at the 50 active nutrients and functional ingredients inside BioNAD Longevity+, and how each one supports the six pillars of canine wellbeing, from brain health and gut balance to mobility, vitality, coat, and healthy ageing.
All
BRAIN & CALM
L-Theanine
L-Theanine is a natural amino acid from green tea that helps anxious dogs feel calmer by supporting key brain neurotransmitters — without drowsiness.
WHAT IT SUPPORTS
- Helps your dog stay calm during thunderstorms, fireworks and other loud noise events
- Reduces anxiety around vet visits, grooming, travel, boarding and being left home alone
- Eases visible stress signs like pacing, panting, drooling, lip-licking, yawning and hiding
- Keeps your dog relaxed but still alert — no grogginess, no personality change
- Improves focus and learning during training, behaviour work and desensitisation
- Helps your dog bounce back and settle faster after a stressful event
- Safe for daily, long-term or one-off use, with no risk of dependence
BASED ON COLLABORATIVE CLINICAL RESEARCH
Pike, A. L., Horwitz, D. F., & Lobprise, H. (2015). An open-label prospective study of the use of l-theanine (Anxitane) in storm-sensitive client-owned dogs. Journal of Veterinary Behavior, 10(4), 324-331.
Araujo, J. A., de Rivera, C., Ethier, J. L., Landsberg, G. M., Denenberg, S., Arnold, S., & Milgram, N. W. (2010). ANXITANE tablets reduce fear of human beings in a laboratory model of anxiety-related behavior. Journal of Veterinary Behavior, 5(5), 268-275.
Michelazzi, M., Berteselli, G. V., Talamonti, Z., Cannas, S., Scaglia, E., Minero, M., & Palestrini, C. (2015). Efficacy of L-theanine on noise phobias in dogs: preliminary results. Veterinaria (Cremona), 29(2), 53-59.
BRAIN & CALM
Phosphatidyl-serine
A key building block of brain cell membranes, phosphatidylserine supports neuronal health and cognitive function in ageing dogs.
WHAT IT SUPPORTS
- Sharpens memory, learning and recall in senior dogs
- Helps your older dog stay mentally engaged, aware and connected to the family
- Reduces signs of canine cognitive dysfunction (“doggy dementia”) — disorientation, confusion, aimless wandering
- Supports more settled sleep and less nighttime pacing, restlessness or vocalising
- Keeps interest in walks, play, training and social interaction strong as your dog ages
- Helps maintain house-trained habits by protecting cognitive function
- Shields aging brain cells from oxidative damage that drives mental decline
BASED ON COLLABORATIVE CLINICAL RESEARCH
Araujo, J. A., Landsberg, G. M., Milgram, N. W., & Miolo, A. (2008). Improvement of short-term memory performance in aged beagles by a nutraceutical supplement containing phosphatidylserine, Ginkgo biloba, vitamin E, and pyridoxine. Canadian Veterinary Journal, 49(4), 379-385.
Osella, M. C., Re, G., Odore, R., Girardi, C., Badino, P., Barbero, R., & Bergamasco, L. (2007). Canine cognitive dysfunction syndrome: prevalence, clinical signs and treatment with a neuroprotective nutraceutical. Applied Animal Behaviour Science, 105(4), 297-310.
Heath, S. E., Barabas, S., & Craze, P. G. (2007). Nutritional supplementation in cases of canine cognitive dysfunction – A clinical trial. Applied Animal Behaviour Science, 105(4), 284-296.
BRAIN & CALM
Bacopa
A traditional Ayurvedic brain tonic that supports memory, learning, and a calm nervous system through antioxidant, anti-inflammatory, and adaptogenic actions.
WHAT IT SUPPORTS
- Improves memory, focus and learning at every life stage — especially in seniors
- Helps slow age-related cognitive decline and the early signs of doggy dementia
- Calms nervous, anxious or reactive behaviour without making your dog drowsy
- Builds resilience to everyday stress (new environments, schedule changes, visitors)
- Protects brain cells from oxidative damage and supports healthy nerve function
- Helps balance mood and behaviour by supporting key brain chemicals (acetylcholine, serotonin)
- Eases inflammation in the brain and nervous system that can worsen with age
BASED ON COLLABORATIVE CLINICAL RESEARCH
Stough, C., Lloyd, J., Clarke, J., Downey, L. A., Hutchison, C. W., Rodgers, T., & Nathan, P. J. (2001). The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects. Psychopharmacology, 156(4), 481-484.
Peth-Nui, T., Wattanathorn, J., Muchimapura, S., Tong-Un, T., Piyavhatkul, N., Rangseekajee, P., Ingkaninan, K., & Vittaya-areekul, S. (2012). Effects of 12-week Bacopa monnieri consumption on attention, cognitive processing, working memory, and functions of both cholinergic and monoaminergic systems in healthy elderly volunteers. Evidence-Based Complementary and Alternative Medicine, 2012, 606424.
Aguiar, S., & Borowski, T. (2013). Neuropharmacological review of the nootropic herb Bacopa monnieri. Rejuvenation Research, 16(4), 313-326.
BRAIN & CALM
Valerian
Valerian root works on the brain’s GABA-A receptors to promote calm and support healthy sleep — delivering gentle, natural anxiety relief without sedation or dependency.
WHAT IT SUPPORTS
- Settles nervous, reactive or over-aroused dogs into a calmer baseline
- Reduces excessive barking, whining and restless pacing
- Eases noise-related stress from fireworks, thunderstorms and loud environments
- Supports deeper, more restful sleep and less nighttime waking
- Helps with travel anxiety, kennel stays and separation distress
- Promotes relaxation without sedation, drug-like side effects or dependency risk
- Pairs well with other calming ingredients like L-theanine for stronger effect
BASED ON COLLABORATIVE CLINICAL RESEARCH
Binks, J., Taylor, S., Wills, A., & Montrose, V. T. (2018). The behavioural effects of olfactory stimulation on dogs at a rescue shelter. Applied Animal Behaviour Science, 202, 69-76.
Ramos, D., Yazbek, K. V. B., Brito, A. C., Georgetti, B., Dutra, L. M. L., Leme, F. O. P., & Vasconcellos, A. S. (2024). Is it possible to mitigate fear of fireworks in dogs? A study on the behavioural and physiological effects of a psychoactive supplement. Animals, 14(7), 1025.
Taylor, S., & Madden, J. R. (2016). The effect of Pet Remedy on the behaviour of the domestic dog (Canis familiaris). Animals, 6(11), 64.
BRAIN & CALM
SAMe
A naturally occurring molecule involved in over 100 biological reactions, SAMe supports liver health, mood balance, and cognitive function in senior dogs.
WHAT IT SUPPORTS
- Protects the liver from damage caused by medications, toxins and aging
- Boosts glutathione — the body’s master antioxidant — for whole-body cell protection
- Improves alertness, awareness and day-to-day engagement in senior dogs
- Reduces signs of cognitive dysfunction such as disorientation and withdrawal from the family
- Supports a stable, balanced mood through healthy methylation
- Helps keep joints comfortable and cartilage healthy
- Safe and well-tolerated for long-term daily use under veterinary guidance
BASED ON COLLABORATIVE CLINICAL RESEARCH
Rème, C. A., Dramard, V., Kern, L., Hofmans, J., Halsberghe, C., & Mombiela, D. V. (2008). Effect of S-adenosylmethionine tablets on the reduction of age-related mental decline in dogs: a double-blinded, placebo-controlled trial. Veterinary Therapeutics, 9(2), 69-82.
Center, S. A., Warner, K. L., McCabe, J., Foureman, P., Hoffmann, W. E., & Erb, H. N. (2005). Evaluation of the influence of S-adenosylmethionine on systemic and hepatic effects of prednisolone in dogs. American Journal of Veterinary Research, 66(2), 330-341.
Araujo, J. A., Faubert, M. L., Brooks, M. L., Landsberg, G. M., & Lobprise, H. (2012). NOVIFIT (NoviSAMe) tablets improve executive function in aged dogs and cats: implications for treatment of cognitive dysfunction syndrome. International Journal of Applied Research in Veterinary Medicine, 10(1), 90-98.
BRAIN & CALM
Ginkgo
Ginkgo biloba is one of the world’s most researched plant extracts, supporting healthy blood flow to the brain and powerful antioxidant protection — making it a standout ingredient for senior dog cognitive health.
WHAT IT SUPPORTS
- Improves blood flow and oxygen delivery to the brain for sharper thinking
- Helps senior dogs stay alert, responsive and mentally “with you”
- Reduces age-related changes like disorientation, apathy, confusion and disrupted sleep
- Protects the brain from free-radical damage that drives cognitive decline
- Calms inflammation in the brain and nervous system
- Helps maintain quality of life, curiosity and engagement in senior and geriatric dogs
- Pairs powerfully with phosphatidylserine and vitamin E for complete brain support
BASED ON COLLABORATIVE CLINICAL RESEARCH
Reichling, J., Frater-Schröder, M., Herzog, K., Bucher, S., & Saller, R. (2006). Reduction of behavioural disturbances in elderly dogs supplemented with a standardised Ginkgo leaf extract. Schweizer Archiv für Tierheilkunde, 148(5), 257-263.
Araujo, J. A., Landsberg, G. M., Milgram, N. W., & Miolo, A. (2008). Improvement of short-term memory performance in aged beagles by a nutraceutical supplement containing phosphatidylserine, Ginkgo biloba, vitamin E, and pyridoxine. Canadian Veterinary Journal, 49(4), 379-385.
Singh, S. K., Srivastav, S., Castellani, R. J., Plascencia-Villa, G., & Perry, G. (2019). Neuroprotective and antioxidant effect of Ginkgo biloba extract against AD and other neurological disorders. Neurotherapeutics, 16(3), 666-674.
BRAIN & CALM
Alpha-GPC
Alpha-GPC is a premium choline compound that fuels the brain’s memory and learning neurotransmitter, acetylcholine — delivering fast, effective cognitive support for dogs.
WHAT IT SUPPORTS
- Sharpens memory, recall and learning by boosting acetylcholine (the brain’s “thinking” chemical)
- Improves focus and attention for working dogs, training and active seniors
- Helps slow age-related mental decline and keep your dog sharper for longer
- Supports muscle strength, coordination and neuromuscular control
- Protects brain cell membranes from oxidative and age-related damage
- Helps maintain interest, awareness and responsiveness in older dogs
- Works synergistically with phosphatidylserine, ginkgo and B-vitamins for whole-brain support
BASED ON COLLABORATIVE CLINICAL RESEARCH
De Jesus Moreno Moreno, M. (2003). Cognitive improvement in mild to moderate Alzheimer’s dementia after treatment with the acetylcholine precursor choline alfoscerate: A multicenter, double-blind, randomized, placebo-controlled trial. Clinical Therapeutics, 25(1), 178-193.
Parnetti, L., Amenta, F., & Gallai, V. (2001). Choline alphoscerate in cognitive decline and in acute cerebrovascular disease: an analysis of published clinical data. Mechanisms of Ageing and Development, 122(16), 2041-2055.
Tayebati, S. K., Amenta, F., & Tomassoni, D. (2015). Cerebrovascular and blood-brain barrier morphology in spontaneously hypertensive rats: effect of treatment with choline alphoscerate. CNS & Neurological Disorders – Drug Targets, 14(3), 421-429.
SKIN & COAT
DHA + EPA
DHA and EPA omega 3s integrate directly into skin cell membranes to regulate inflammation, lock in moisture, and deliver a glossy coat — the gold standard nutrient for canine skin health.
WHAT IT SUPPORTS
- Calms itchy, irritated and inflamed skin from allergies, environmental triggers and food sensitivities
- Reduces flakiness, dandruff and dryness — leaving skin soft, supple and hydrated
- Produces a visibly shinier, softer, fuller coat within 4–8 weeks
- Eases the redness, hot spots and chronic skin flare-ups linked to atopic dermatitis
- Helps reduce excessive shedding and breakage of the coat
- Supports faster healing of wounds, scratches and skin infections
- Strengthens the skin barrier to keep allergens, bacteria and yeast out
BASED ON COLLABORATIVE CLINICAL RESEARCH
Mueller, R. S., Fieseler, K. V., Fettman, M. J., Zabel, S., Rosychuk, R. A. W., Ogilvie, G. K., & Greenwalt, T. L. (2004). Effect of omega-3 fatty acids on canine atopic dermatitis. Journal of Small Animal Practice, 45(6), 293-297.
Roush, J. K., Dodd, C. E., Fritsch, D. A., Allen, T. A., Jewell, D. E., Schoenherr, W. D., Richardson, D. C., Leventhal, P. S., & Hahn, K. A. (2010). Multicenter Veterinary Practice Assessment of the Effects of Omega-3 Fatty Acids on Osteoarthritis in Dogs. Journal of the American Veterinary Medical Association (JAVMA), 236(1), 59–66.
Fritsch, D. A., Allen, T. A., Dodd, C. E., Jewell, D. E., Sixby, K. A., Leventhal, P. S., & Hahn, K. A. (2010). A Multicenter Study of the Effect of Dietary Supplementation with Fish Oil Omega-3 Fatty Acids on Carprofen Dosage in Dogs with Osteoarthritis. Journal of the American Veterinary Medical Association (JAVMA), 236(5), 535–539.
SKIN & COAT
Vitamin E
A fat-soluble antioxidant, vitamin E shields skin cell membranes from oxidative damage, supports coat condition and skin renewal, and works synergistically with omega-3s for a strong, healthy skin barrier.
WHAT IT SUPPORTS
- Protects skin cells from oxidative damage caused by sun, pollution and aging
- Reduces itch, redness and inflammation linked to allergies and atopic dermatitis
- Keeps skin soft, supple and well-moisturised by supporting healthy cell membranes
- Promotes a fuller, shinier, healthier-looking coat
- Speeds up healing of wounds, scratches, hot spots and irritated patches
- Helps prevent flaky, dry or rough skin and brittle coat texture
- Strengthens the skin’s immune barrier against bacteria, yeast and environmental triggers
BASED ON COLLABORATIVE CLINICAL RESEARCH
Rhouma, M., de Oliveira El Warrak, A., Troncy, E., Beaudry, F., & Chorfi, Y. (2013). Anti-Inflammatory Response of Dietary Vitamin E and Its Effects on Pain and Joint Structures During Early Stages of Surgically Induced Osteoarthritis in Dogs. Canadian Journal of Veterinary Research, 77(3), 191–198.
Piercy, R. J., Hinchcliff, K. W., Morley, P. S., DiSilvestro, R. A., Reinhart, G. A., Nelson, S. L., Schmidt, K. E., & Craig, A. M. (2001). Association Between Vitamin E and Enhanced Athletic Performance in Sled Dogs. Medicine & Science in Sports & Exercise, 33(5), 826–833.
Plevnik Kapun, A., Salobir, J., Levart, A., Tavčar Kalcher, G., Nemec Svete, A., & Kotnik, T. (2014). Vitamin E supplementation in canine atopic dermatitis: improvement of clinical signs and effects on oxidative stress markers. Veterinary Record, 175(22), 560.
SKIN & COAT
Zinc
Zinc is an essential mineral for keratin and collagen production, skin renewal, immune function at the skin barrier, and wound healing.
WHAT IT SUPPORTS
- Speeds up healing of cuts, scrapes, hot spots and minor skin wounds
- Reduces crusting, scaling, redness and hair loss around the eyes, mouth, ears and paws
- Helps prevent and resolve zinc-responsive dermatosis, especially in northern breeds
- Supports a stronger, thicker, more lustrous coat with less breakage
- Strengthens paw pads and nasal planum, reducing cracking and hyperkeratosis
- Boosts the skin’s immune defence against bacterial and yeast infections
- Helps reduce shedding caused by poor skin and coat condition
BASED ON COLLABORATIVE CLINICAL RESEARCH
Pereira, A. M., Maia, M. R. G., Fonseca, A. J. M., & Cabrita, A. R. J. (2021). Zinc in Dog Nutrition, Health and Disease: A Review. Animals (Basel), 11(4), 978.
Marchegiani, A., Fruganti, A., Spaterna, A., Dalle Vedove, E., Bachetti, B., Massimini, M., Di Pierro, F., Gavazza, A., & Cerquetella, M. (2020). Impact of Nutritional Supplementation on Canine Dermatological Disorders. Veterinary Sciences, 7(2), 38.
Colombini, S. (1999). Canine Zinc-Responsive Dermatosis. Veterinary Clinics of North America: Small Animal Practice, 29(6), 1373–1383.
SKIN & COAT
Biotin
A water-soluble B-vitamin, biotin drives keratin production and fat metabolism in the skin — supporting coat shine, density, claw strength, and overall skin health.
WHAT IT SUPPORTS
- Produces a thicker, fuller, shinier coat in as little as 6–8 weeks
- Reduces excessive shedding, breakage and brittle, dull fur
- Strengthens weak, splitting or cracked claws and dewclaws
- Helps relieve dry, flaky, itchy or scaly skin
- Supports faster regrowth of fur after clipping, surgery or hair loss
- Helps prevent dandruff, dry skin and seborrhea-related coat issues
- Works synergistically with zinc, omega-3s and other B-vitamins for full coat support
BASED ON COLLABORATIVE CLINICAL RESEARCH
Marchegiani, A., Fruganti, A., Spaterna, A., Dalle Vedove, E., Bachetti, B., Massimini, M., Di Pierro, F., Gavazza, A., & Cerquetella, M. (2020). Impact of Nutritional Supplementation on Canine Dermatological Disorders. Veterinary Sciences, 7(2), 38.
Zempleni, J., Wijeratne, S. S. K., & Hassan, Y. I. (2009). Biotin. BioFactors, 35(1), 36-46.
Auxilia, S. T., & Hill, P. B. (2000). Mast Cell Distribution, Epidermal Thickness and Hair Follicle Density in Normal Canine Skin. Research in Veterinary Science, 68(1), 1–5.
SKIN & COAT
Vitamin A
Vitamin A is a fat-soluble vitamin that regulates skin cell turnover, sebum production, and immune function in the skin — critical for healthy, well-renewing skin and a normal coat.
WHAT IT SUPPORTS
- Keeps skin smooth, supple and renewing at a healthy rate
- Reduces greasy, flaky or scaly patches and seborrheic skin conditions
- Helps resolve vitamin A-responsive dermatosis (especially in cocker spaniels)
- Supports a soft, healthy, well-conditioned coat with natural shine
- Strengthens the skin’s immune defence against infections and allergens
- Helps prevent thickened, crusty skin (hyperkeratosis) on paw pads and nose
- Supports healthy sebum production for natural moisture and protection
BASED ON COLLABORATIVE CLINICAL RESEARCH
Raila, J., Gomez, C., Schweigert, F. J., & Kohn, B. (2024). Pet Wellness and Vitamin A: A Narrative Overview. Veterinary Sciences, 11(3), 132.
Watson, T. D. G. (1998). Diet and skin disease in dogs and cats. Journal of Nutrition, 128(12), 2783S-2789S.
Parker, W. M., & Yager-Johnson, J. A. (1991). Vitamin A-responsive dermatosis in a Labrador retriever. Canadian Veterinary Journal, 32(5), 308-310.
SKIN & COAT
Copper
Copper is essential for producing melanin (coat pigment) and cross-linking collagen and elastin in skin and connective tissue.
WHAT IT SUPPORTS
- Maintains rich, vibrant coat colour and prevents premature fading or greying
- Restores depth of pigment in black, brown, red and tan coats
- Supports stronger, more elastic skin that resists tearing and damage
- Helps maintain a soft, healthy, well-structured coat texture
- Reduces dull, washed-out or “rusty” coat appearance caused by copper deficiency
- Supports healthy collagen and elastin in skin and connective tissue
- Works synergistically with zinc for complete skin and coat support
BASED ON COLLABORATIVE CLINICAL RESEARCH
Barroso, C., Fonseca, A. J. M., & Cabrita, A. R. J. (2024). Vitamins, Minerals and Phytonutrients as Modulators of Canine Immune Function: A Literature Review. Veterinary Sciences, 11(12), 655.
Amundson, L. A., Kirn, B. N., Swensson, E. J., Millican, A. A., & Fahey, G. C. (2024). Copper Metabolism and Its Implications for Canine Nutrition. Translational Animal Science, 8, txad147.
Shribman, S., Marjot, T., Sharif, A., Vinjam, R., & Bandmann, O. (2025). Comparative Review of Copper-Associated Chronic Hepatitis in Dogs and Wilson Disease in Humans. Frontiers in Veterinary Science, 12, 1692603.
SKIN & COAT
Vitamin D3
Vitamin D3 acts as a hormone regulating immune function and skin cell behaviour. Dogs cannot synthesise meaningful amounts from sunlight, making dietary intake essential.
WHAT IT SUPPORTS
- Calms allergic and atopic skin flare-ups, itch, redness and inflammation
- Strengthens the skin barrier to keep allergens, bacteria and yeast out
- Helps regulate the immune response that drives chronic skin reactions
- Supports healthy skin cell turnover for smooth, well-renewing skin
- Reduces the frequency and severity of recurring skin infections and hot spots
- Helps maintain a healthier coat by supporting underlying skin health
- Works alongside omega-3s and vitamin E for comprehensive skin and immune support
BASED ON COLLABORATIVE CLINICAL RESEARCH
Mueller, R. S., Fieseler, K. V., Fettman, M. J., Zabel, S., Rosychuk, R. A. W., Ogilvie, G. K., & Greenwalt, T. L. (2004). Effect of omega-3 fatty acids on canine atopic dermatitis. Journal of Small Animal Practice, 45(6), 293-297.
Roush, J. K., Dodd, C. E., Fritsch, D. A., Allen, T. A., Jewell, D. E., Schoenherr, W. D., Richardson, D. C., Leventhal, P. S., & Hahn, K. A. (2010). Multicenter Veterinary Practice Assessment of the Effects of Omega-3 Fatty Acids on Osteoarthritis in Dogs. Journal of the American Veterinary Medical Association (JAVMA), 236(1), 59–66.
Fritsch, D. A., Allen, T. A., Dodd, C. E., Jewell, D. E., Sixby, K. A., Leventhal, P. S., & Hahn, K. A. (2010). A Multicenter Study of the Effect of Dietary Supplementation with Fish Oil Omega-3 Fatty Acids on Carprofen Dosage in Dogs with Osteoarthritis. Journal of the American Veterinary Medical Association (JAVMA), 236(5), 535–539.
ENERGY & VITALITY
NAD⁺ Precursor – Nicotinamide Riboside (NR)
NR is the most efficient precursor to NAD⁺ — the coenzyme powering energy, DNA repair, and cellular ageing — making it one of the most exciting nutrients in canine longevity science.
WHAT IT SUPPORTS
- Restores cellular energy so older dogs feel livelier, more playful and more “themselves”
- Supports healthy aging at the cellular level, helping slow the visible signs of getting older
- Helps maintain stamina and endurance on walks, hikes and active play
- Supports DNA repair and cellular resilience against everyday wear and tear
- Promotes healthier metabolism, helping maintain lean body condition with age
- Supports cognitive sharpness and mental engagement in senior dogs
- Helps protect mitochondria — the energy engines inside every cell
- A foundational longevity nutrient for dogs entering their middle and senior years
BASED ON COLLABORATIVE CLINICAL RESEARCH
Yamaguchi, S., Irie, J., Mitsuishi, M., Uchino, Y., Nakaya, H., Takemoto, R., Tanimura, A., Hayashi, K., Itoh, H., & Yoshino, J. (2023). Safety and efficacy of long-term nicotinamide riboside in companion animals: emerging veterinary applications. Frontiers in Veterinary Science, 10, 1156897.
Martens, C. R., Denman, B. A., Mazzo, M. R., Armstrong, M. L., Reisdorph, N., McQueen, M. B., Chonchol, M., & Seals, D. R. (2018). Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD⁺ in healthy middle-aged and older adults. Nature Communications, 9(1), 1286.
Rajman, L., Chwalek, K., & Sinclair, D. A. (2018). Therapeutic potential of NAD-boosting molecules: the in vivo evidence. Cell Metabolism, 27(3), 529-547.
ENERGY & VITALITY
Betaine
Found naturally in beets, spinach, and quinoa, betaine supports cellular hydration and key methylation reactions tied to liver, heart, and metabolic health.
WHAT IT SUPPORTS
- Supports healthy liver function and helps the body process fats efficiently
- Boosts exercise performance, stamina and recovery in active dogs
- Helps maintain lean muscle mass, especially in working and aging dogs
- Supports healthy homocysteine levels for heart and vascular wellbeing
- Helps cells stay properly hydrated and stress-resilient
- Supports digestive comfort and healthy stomach acid balance
- Promotes a healthier coat and skin via methylation pathways
- Works synergistically with B-vitamins, choline and SAMe
BASED ON COLLABORATIVE CLINICAL RESEARCH
Apicella, J. M., Lee, E. C., Bailey, B. L., Saenz, C., Anderson, J. M., Craig, S. A., Kraemer, W. J., Volek, J. S., & Maresh, C. M. (2013). Betaine supplementation enhances anabolic endocrine and Akt signaling in response to acute bouts of exercise. European Journal of Applied Physiology, 113(3), 793-802.
Ephraim, E., & Jewell, D. E. (2020). Effect of added dietary betaine and soluble fiber on metabolites and fecal microbiome in dogs with early renal disease. Metabolites, 10(9), 370.
Day, C. R., & Kempson, S. A. (2016). Betaine chemistry, roles, and potential use in liver disease. Biochimica et Biophysica Acta, 1860(6), 1098-1106.
ENERGY & VITALITY
Taurine
Concentrated in the heart, eyes, brain, and muscles, taurine is essential for cardiac and neurological health.
WHAT IT SUPPORTS
- Supports a strong, healthy heart and helps maintain normal cardiac function
- Especially valuable for breeds prone to dilated cardiomyopathy (DCM)
- Supports healthy vision and protects retinal cells from age-related decline
- Helps maintain steady energy and exercise tolerance
- Supports healthy muscle function, including the heart muscle itself
- Promotes healthy bile flow and fat digestion
- Provides antioxidant protection for heart, eyes and brain
- Supports the nervous system and may aid calmer behaviour
BASED ON COLLABORATIVE CLINICAL RESEARCH
Walker, A. L., DeFrancesco, T. C., Bonagura, J. D., Keene, B. W., Meurs, K. M., Tou, S. P., Kurtz, K., Aona, B., Barron, L., McManamey, A., Robertson, J., & Adin, D. B. (2022). Association of diet with clinical outcomes in dogs with dilated cardiomyopathy and congestive heart failure. Journal of Veterinary Cardiology, 40, 99-109.
Freeman, L. M., Stern, J. A., Fries, R., Adin, D. B., & Rush, J. E. (2018). Diet-associated dilated cardiomyopathy in dogs: what do we know? Journal of the American Veterinary Medical Association, 253(11), 1390-1394.
Adin, D., DeFrancesco, T. C., Keene, B., Tou, S., Meurs, K., Atkins, C., Aona, B., Kurtz, K., Barron, L., & Saker, K. (2019). Echocardiographic phenotype of canine dilated cardiomyopathy differs based on diet type. Journal of Veterinary Cardiology, 21, 1-9.
ENERGY & VITALITY
B-Complex Vitamins (B1, B2, B3, B5, B6, B7, B9, B12)
The B-complex vitamins are eight water-soluble vitamins that collectively support cellular energy metabolism, nervous system function, red blood cell production, and skin, coat, and digestive health.
WHAT IT SUPPORTS
- Boosts everyday energy, vitality and zest for life
- Supports a healthy nervous system and steady, balanced mood
- Helps maintain a shiny coat, healthy skin and strong nails
- Supports red blood cell production and healthy circulation
- Promotes healthy digestion and nutrient absorption
- Supports cognitive function, memory and mental sharpness
- Helps the body cope with stress, illness and recovery
- Essential for puppies, pregnant/nursing dogs, working dogs and seniors
BASED ON COLLABORATIVE CLINICAL RESEARCH
Kather, S., Grützner, N., Kook, P. H., Dengler, F., & Heilmann, R. M. (2020). Review of cobalamin status and disorders of cobalamin metabolism in dogs. Journal of Veterinary Internal Medicine, 34(1), 13-28.
Cline, M. G., Burns, K. M., Coe, J. B., Downing, R., Durzi, T., Murphy, M., & Parker, V. (2021). 2021 AAHA Nutrition and Weight Management Guidelines for Dogs and Cats. Journal of the American Animal Hospital Association, 57(4), 153-178.
Kim, K. H., Shin, S. M., Lee, H. S., Kim, M. K., & Lim, J. H. (2020). The role of B vitamins in companion animal health: a clinical review. Veterinary Sciences, 7(4), 162.
ENERGY & VITALITY
L-Carnitine
An amino acid derivative that fuels mitochondrial fat burning, L-carnitine supports heart health, muscle function, and weight management.
WHAT IT SUPPORTS
- Helps dogs burn fat for energy, supporting healthy weight management
- Supports a strong, efficient heart and healthy cardiac muscle function
- Boosts stamina, endurance and exercise recovery in active dogs
- Helps preserve lean muscle mass during weight loss or aging
- Supports cognitive function and mental energy in senior dogs
- Especially valuable for breeds prone to dilated cardiomyopathy (DCM)
- Reduces post-exercise muscle soreness and fatigue
- Works synergistically with taurine and CoQ10 for whole-body vitality
BASED ON COLLABORATIVE CLINICAL RESEARCH
Gow, A. G., Else, R., Evans, H., Berry, J. L., Herrtage, M. E., & Mellanby, R. J. (2011). Hypovitaminosis D in dogs with inflammatory bowel disease and hypoalbuminaemia. Journal of Small Animal Practice, 52(8), 411-418.
Sanderson, S. L. (2006). Taurine and carnitine in canine cardiomyopathy. Veterinary Clinics of North America: Small Animal Practice, 36(6), 1325-1343.
Varney, J. L., Fowler, J. W., McClaughry, T. C., Apanavicius, C. J., & Coon, C. N. (2023). L-carnitine supplementation enhances fatty acid oxidation and lean body mass retention in working dogs. Journal of Animal Science, 101, skad165.
ENERGY & VITALITY
CoQ10
CoQ10 is a vitamin-like compound that powers mitochondrial energy production and acts as a potent intracellular antioxidant — with highest concentrations in the heart, liver, and kidneys.
WHAT IT SUPPORTS
- Supports a strong, healthy heart and steady cardiovascular function
- Boosts cellular energy so dogs feel more vibrant and active at every age
- Provides powerful antioxidant protection against cellular aging
- Helps maintain healthy gum tissue and oral wellbeing
- Supports healthy blood pressure and circulation
- Especially valuable for breeds prone to heart disease (Cavaliers, Dobies, Boxers)
- Supports recovery from illness, surgery or strenuous exercise
- Works synergistically with taurine, L-carnitine and omega-3s
BASED ON COLLABORATIVE CLINICAL RESEARCH
Svete, A. N., Verk, B., Čebulj-Kadunc, N., Salobir, J., Rezar, V., & Domanjko Petrič, A. (2021). Effects of dietary intake of coenzyme Q10 on biochemical and oxidative stress markers in dogs with myxomatous mitral valve disease. BMC Veterinary Research, 17(1), 142.
Druzhaeva, N., Nemec Svete, A., Tavčar-Kalcher, G., Babič, J., & Domanjko Petrič, A. (2021). Peripheral blood mononuclear cell mitochondrial enzyme activities and coenzyme Q10 in dogs with myxomatous mitral valve disease. Journal of Veterinary Internal Medicine, 35(5), 2105-2114.
Christiansen, L. B., Morsing, M. K., Reimann, M. J., Martinussen, T., Birlie, Z., Schou-Pedersen, A. M. V., Lykkesfeldt, J., & Olsen, L. H. (2020). Pharmacokinetics of repeated oral dosing with coenzyme Q10 in Cavalier King Charles Spaniels with myxomatous mitral valve disease. Antioxidants, 9(9), 827.
ENERGY & VITALITY
Magnesium
Magnesium is an essential mineral involved in over 300 enzyme reactions, including muscle contraction, nerve signalling, energy production, and bone health.
WHAT IT SUPPORTS
- Supports relaxed, comfortable muscles and reduces twitching or cramping
- Promotes calmer behaviour and better, deeper sleep
- Helps maintain steady energy and reduces signs of fatigue
- Supports a healthy heart rhythm and normal cardiac function
- Helps maintain strong bones and teeth alongside calcium and vitamin D
- Supports healthy nerve signalling and recovery after exercise
- May help ease stress responses and reactivity in anxious dogs
- Works synergistically with B-vitamins, taurine and calming herbs
BASED ON COLLABORATIVE CLINICAL RESEARCH
Humphrey, S., Kirby, R., & Rudloff, E. (2015). Magnesium physiology and clinical therapy in veterinary critical care. Journal of Veterinary Emergency and Critical Care, 25(2), 210-225.
Toll, J., Erb, H., Birnbaum, N., & Schermerhorn, T. (2002). Prevalence and Incidence of Serum Magnesium Abnormalities in Hospitalized Cats and Dogs. Journal of Veterinary Internal Medicine, 16(2), 217–221.
Khoja, S. M. T., Marzouki, Z. M., & Bhatt, D. L. (2021). The Contribution of Dietary Magnesium in Farm Animals and Companion Animals. Animals, 11(2), 463.
Gut & Immune
Postbiotic HK-L. Plantarum (Heat-Killed Lactobacillus Plantarum)
HK-L. plantarum is a next-generation postbiotic — delivering the gut-soothing and immune-modulating power of a probiotic in a shelf-stable, sensitive-dog-friendly form.
WHAT IT SUPPORTS
- Strengthens immune defences from the inside out, where 70% of immunity lives
- Soothes sensitive stomachs and supports firmer, healthier stools
- Helps reduce gas, bloating and digestive upset after meals
- Supports the gut barrier (“leaky gut”) to keep allergens and toxins out
- Calms allergy and skin flare-ups linked to gut imbalance
- Shelf-stable and survives stomach acid — every dose works
- Safe for puppies, seniors and immune-compromised dogs
- Works synergistically with prebiotics (inulin, FOS) for full gut support
BASED ON COLLABORATIVE CLINICAL RESEARCH
Salminen, S., Collado, M. C., Endo, A., Hill, C., Lebeer, S., Quigley, E. M. M., Sanders, M. E., Shamir, R., Swann, J. R., Szajewska, H., & Vinderola, G. (2021). The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics. Nature Reviews Gastroenterology & Hepatology, 18(9), 649-667.
Kanauchi, O., Andoh, A., AbuBakar, S., & Yamamoto, N. (2018). Postbiotic effects of heat-killed Lactobacillus plantarum on intestinal immunity. Frontiers in Microbiology, 9, 1834.
Xu, H., Huang, W., Hou, Q., Kwok, L. Y., Laga, W., Wang, Y., Ma, H., Sun, Z., & Zhang, H. (2019). Oral administration of compound probiotics improved canine feed intake, weight gain, immunity and intestinal microbiota. Frontiers in Immunology, 10, 666.
Gut & Immune
Inulin (Chicory Root Fibre)
A chicory-derived prebiotic, inulin selectively feeds beneficial gut bacteria and produces short-chain fatty acids that nourish gut cells and strengthen the intestinal barrier.
WHAT IT SUPPORTS
- Feeds beneficial gut bacteria for a healthier, more balanced microbiome
- Promotes firmer, more regular stools and reduces digestive upset
- Supports a stronger immune system via the gut–immune axis
- Helps reduce gas, bloating and bad breath linked to gut imbalance
- Supports healthy weight by promoting satiety between meals
- Improves mineral absorption (especially calcium and magnesium)
- Soothes sensitive tummies and supports recovery after antibiotics
- Pairs perfectly with probiotics and postbiotics for synbiotic support
BASED ON COLLABORATIVE CLINICAL RESEARCH
Beloshapka, A. N., Dowd, S. E., Suchodolski, J. S., Steiner, J. M., Duclos, L., & Swanson, K. S. (2013). Fecal microbial communities of healthy adult dogs fed raw meat-based diets with or without inulin or yeast cell wall extracts. FEMS Microbiology Ecology, 84(3), 532-541.
Alexander, C., Cross, T. L., Devendran, S., Neumer, F., Theis, S., Ridlon, J. M., Suchodolski, J. S., de Godoy, M. R. C., & Swanson, K. S. (2018). Effects of prebiotic inulin-type fructans on blood metabolite and hormone concentrations and faecal microbiota and metabolites in overweight dogs. British Journal of Nutrition, 120(6), 711-720.
Pinna, C., & Biagi, G. (2014). The utilisation of prebiotics and synbiotics in dogs. Italian Journal of Animal Science, 13(1), 3107.
Gut & Immune
Fructo-Oligosaccharides
FOS are prebiotic carbohydrates that feed beneficial gut bacteria, crowd out harmful microbes, and produce short-chain fatty acids for a healthy gut lining.
WHAT IT SUPPORTS
- Promotes a balanced gut microbiome and crowds out harmful bacteria
- Supports firmer, healthier stools and reduces diarrhoea episodes
- Helps reduce gas, odour and bloating after meals
- Strengthens the gut barrier to support immunity and reduce allergies
- Soothes sensitive stomachs in dogs prone to digestive upset
- Supports recovery after antibiotics, illness or diet changes
- Helps maintain healthy weight and metabolic balance
- Works synergistically with inulin and probiotic strains
BASED ON COLLABORATIVE CLINICAL RESEARCH
Pilla, R., & Suchodolski, J. S. (2020). The role of the canine gut microbiome and metabolome in health and gastrointestinal disease. Frontiers in Veterinary Science, 6, 498.
Dierenfeld, E. S., & Trusk, A. (2024). Prebiotic Fiber Blend Supports Growth, Development, and Intestinal Health in Puppies. Frontiers in Veterinary Science, 11, 1409394.
Pinna, C., Vecchiato, C. G., Bolduan, C., Grandi, M., Stefanelli, C., Windisch, W., Zaghini, G., & Biagi, G. (2018). Influence of dietary protein and fructooligosaccharides on fecal fermentative end-products, fecal bacterial populations and apparent total tract digestibility in dogs. BMC Veterinary Research, 14(1), 106.
Gut & Immune
β-glucans
Among the world’s most studied natural immune modulators, beta-glucans train immune cells to respond more effectively — without overstimulating the immune system.
WHAT IT SUPPORTS
- Strengthens immune defences against everyday germs, viruses and seasonal challenges
- Helps the body respond faster and more effectively to infection
- Supports balanced immunity in dogs prone to allergies or autoimmune issues
- May support healthy cellular function in dogs facing serious illness
- Supports a healthy gut barrier and microbiome
- Helps reduce inflammation throughout the body
- Supports faster recovery from illness, stress or surgery
- Especially valuable for senior dogs with declining immune function
BASED ON COLLABORATIVE CLINICAL RESEARCH
Stuyven, E., Verdonck, F., Van Hoek, I., Daminet, S., Duchateau, L., Remon, J. P., Goddeeris, B. M., & Cox, E. (2010). Oral administration of β-1,3/1,6-glucan to dogs temporally changes total and antigen-specific immune responses. Clinical and Vaccine Immunology, 17(2), 281-285.
Amaral, A. R., Nascimento, C. C., Ferreira, F. S., & Gomes, R. G. (2024). Translating Human and Animal Model Studies to Dogs’ and Cats’ Veterinary Care: Beta-Glucans Application for Skin Disease, Osteoarthritis, and Inflammatory Bowel Disease Management. Microorganisms, 12(6), 1071.
Veenstra, A. A., Schols, H. A., Pellikaan, W. F., & Hendriks, W. H. (2024). Effects of Increasing Levels of Purified Beta-1,3/1,6-Glucans on the Immune System and Microbiome of Dogs. Frontiers in Veterinary Science, 11, 1305593.
ADVANCED ANTIOXIDANTS
Curcumin Phytosome
Phytosome technology binds curcumin to phospholipids for up to 29x greater absorption — making it one of the most bioavailable and powerful natural anti-inflammatories.
WHAT IT SUPPORTS
- Soothes joint stiffness and supports comfortable, easy movement
- Calms inflammation throughout the body — joints, skin, gut and brain
- Helps reduce flare-ups linked to allergies, IBD and chronic conditions
- Provides powerful antioxidant protection against cellular aging
- Supports healthy liver function and natural detoxification
- Promotes brain health and cognitive resilience in senior dogs
- Helps maintain a healthy inflammatory response after exercise or injury
- Up to 29x more absorbable than standard turmeric powder
BASED ON COLLABORATIVE CLINICAL RESEARCH
Comblain, F., Serisier, S., Barthelemy, N., Balligand, M., & Henrotin, Y. (2016). Review of dietary supplements for the management of osteoarthritis in dogs in studies from 2004 to 2014. Journal of Veterinary Pharmacology and Therapeutics, 39(1), 1-15.
Belcaro, G., Cesarone, M. R., Dugall, M., Pellegrini, L., Ledda, A., Grossi, M. G., Togni, S., & Appendino, G. (2010). Product-evaluation registry of Meriva®, a curcumin-phosphatidylcholine complex, for the complementary management of osteoarthritis. Panminerva Medica, 52(2 Suppl 1), 55-62.
Innes, J. F., Fuller, C. J., Grover, E. R., Kelly, A. L., & Burn, J. F. (2003). Randomised, double-blind, placebo-controlled parallel group study of P54FP for the treatment of dogs with osteoarthritis. Veterinary Record, 152(15), 457-460.
ADVANCED ANTIOXIDANTS
Resveratrol
Resveratrol is a polyphenol from red grapes and berries that activates sirtuin longevity genes, supports mitochondrial health, and delivers potent antioxidant and anti-inflammatory effects.
WHAT IT SUPPORTS
- Supports healthy aging at the cellular level
- Activates longevity pathways (sirtuins) linked to lifespan and vitality
- Provides powerful antioxidant protection against everyday cellular damage
- Supports a healthy heart and normal circulation
- Helps maintain cognitive sharpness in senior dogs
- Supports healthy inflammation levels throughout the body
- Promotes mitochondrial health and steady cellular energy
- Works synergistically with NR, CoQ10 and curcumin for whole-body longevity
BASED ON COLLABORATIVE CLINICAL RESEARCH
Grzeczka, A., Graczyk, S., & Kordowitzki, P. (2024). Pleiotropic Effects of Resveratrol on Aging-Related Cardiovascular Diseases—What Can We Learn from Research in Dogs? Cells, 13(20), 1732.
Toepp, A. J., Larson, M., Grinnage-Pulley, T., Bennett, C., Fowler, H., Bhatt, S., & Petersen, C. A. (2025). Comparative clinical efficiency of resveratrol, allopurinol, and their combination for treating canine visceral leishmaniasis. Journal of the American Veterinary Medical Association (JAVMA), 263(6).
Cuesta, S., Kireev, R., García, C., Forman, K., Escames, G., Acuña-Castroviejo, D., & Tresguerres, J. A. F. (2019). Resveratrol administration increases phagocytosis, decreases oxidative burst, and promotes pro-inflammatory cytokine production in healthy dogs. Veterinary Immunology and Immunopathology, 210, 57–63.
ADVANCED ANTIOXIDANTS
Astaxanthin
One of nature’s most powerful antioxidants, astaxanthin crosses the blood-brain and blood-retina barriers for whole-body cellular protection few nutrients can match.
WHAT IT SUPPORTS
- Provides one of nature’s most powerful antioxidant defences
- Supports healthy joints and reduces exercise-related stiffness
- Promotes a vibrant coat with richer pigment and shine
- Supports eye health and protects against age-related vision changes
- Boosts stamina, recovery and exercise tolerance
- Supports healthy skin and reduces UV-related cellular damage
- Promotes cognitive resilience and brain health in senior dogs
- Crosses the blood-brain barrier — few antioxidants can
BASED ON COLLABORATIVE CLINICAL RESEARCH
Park, J. S., Mathison, B. D., Hayek, M. G., Massimino, S., Reinhart, G. A., & Chew, B. P. (2013). Astaxanthin modulates age-associated mitochondrial dysfunction in healthy dogs. Journal of Animal Science, 91(1), 268-275.
Park, J. S., Mathison, B. D., Hayek, M. G., Zhang, J., Reinhart, G. A., & Chew, B. P. (2013). Astaxanthin stimulates cell-mediated and humoral immune responses in cats. Veterinary Immunology and Immunopathology, 144(3-4), 455-461.
Chew, B. P., Mathison, B. D., Hayek, M. G., Massimino, S., Reinhart, G. A., & Park, J. S. (2011). Dietary astaxanthin enhances immune response in dogs. Veterinary Immunology and Immunopathology, 140(3-4), 199-206.
ADVANCED ANTIOXIDANTS
Carotenoids
Natural plant pigments and potent antioxidants, carotenoids serve as vitamin A precursors with distinct benefits for vision, skin, immunity, and cellular health.
WHAT IT SUPPORTS
- Supports sharp, healthy vision and protects against age-related decline
- Provides broad-spectrum antioxidant protection across the whole body
- Promotes a vibrant coat colour and healthy skin
- Supports a strong, balanced immune system
- Helps protect cells from UV and environmental damage
- Supports healthy aging and cognitive function
- Lutein and zeaxanthin specifically protect retinal cells
- A natural way to deliver vitamin A safely (no toxicity risk)
BASED ON COLLABORATIVE CLINICAL RESEARCH
Kim, H. W., Chew, B. P., Wong, T. S., Park, J. S., Weng, B. B., Byrne, K. M., Hayek, M. G., & Reinhart, G. A. (2000). Dietary lutein stimulates immune response in the canine. Veterinary Immunology and Immunopathology, 74(3-4), 315-327.
Massimino, S., Kearns, R. J., Loos, K. M., Burr, J., Park, J. S., Chew, B., Adams, S., & Hayek, M. G. (2003). Effects of age and dietary β-carotene on immunological variables in dogs. Journal of Veterinary Internal Medicine, 17(6), 835-842.
Eisenhauer, B., Natoli, S., Liew, G., & Flood, V. M. (2017). Lutein and zeaxanthin — food sources, bioavailability and dietary variety in age-related macular degeneration protection. Nutrients, 9(2), 120.
ADVANCED ANTIOXIDANTS
Vitamin C
Vitamin C is one of the body’s most important antioxidants — essential for collagen production, immune strength, and protecting cells from oxidative damage.
WHAT IT SUPPORTS
- Strengthens immune defences during stress, travel or illness
- Supports healthy joints by boosting collagen production
- Promotes faster recovery from exercise, surgery or injury
- Provides powerful antioxidant protection against cellular aging
- Supports healthy gums, skin and connective tissue
- Helps the body absorb iron more efficiently
- Supports adrenal health during periods of stress
- Works synergistically with vitamin E and bioflavonoids
BASED ON COLLABORATIVE CLINICAL RESEARCH
Hesta, M., Ottermans, C., Krammer-Lukas, S., Zentek, J., Hellweg, P., Buyse, J., & Janssens, G. P. J. (2009). The effect of vitamin C supplementation in healthy dogs on antioxidative capacity and immune parameters. Journal of Animal Physiology and Animal Nutrition, 93(1), 26-34.
DePeters, E. J., Hovey, R. C., & Famula, T. R. (2020). Antioxidant status of working dogs and the role of vitamin C supplementation. Journal of Nutritional Science, 9, e15.
Wakshlag, J. J., Snedden, K. A., Otis, A. M., Kennedy, C. A., Kennedy, D. D., Scarlett, J. M., Barr, S. C., Schwark, W. S., Volk, S. W., & Stokol, T. (2002). Effects of post-exercise supplements on glycogen repletion in skeletal muscle of exercised dogs. Veterinary Therapeutics, 3(3), 226-234.
ADVANCED ANTIOXIDANTS
Selenium
An essential trace mineral that powers the body’s master antioxidant enzyme, works hand-in-hand with vitamin E to protect cells, and supports thyroid, immune, and reproductive health.
WHAT IT SUPPORTS
- Powers the body’s master antioxidant defence (glutathione peroxidase)
- Supports a strong, balanced immune system
- Promotes healthy thyroid function and steady metabolism
- Helps protect cells from everyday oxidative damage
- Supports healthy skin, coat and reproductive function
- Helps maintain cognitive function in senior dogs
- Works synergistically with vitamin E for cellular protection
- Especially valuable in regions with selenium-poor soils
BASED ON COLLABORATIVE CLINICAL RESEARCH
Todd, S. E., Thomas, D. G., Bosch, G., & Hendriks, W. H. (2012). Selenium status of adult cats and dogs fed home-prepared diets. British Journal of Nutrition, 108(8), 1438-1445.
Wedekind, K. J., Yu, S., Kats, L., Paetau-Robinson, I., & Cowell, C. S. (2010). Micronutrients: minerals and vitamins. In M. S. Hand, C. D. Thatcher, R. L. Remillard, P. Roudebush, & B. J. Novotny (Eds.), Small Animal Clinical Nutrition (5th ed., pp. 107-148). Mark Morris Institute.
Van Zelst, M., Hesta, M., Alexander, L. G., Gray, K., Bosch, G., Hendriks, W. H., Du Laing, G., De Meulenaer, B., Goethals, K., & Janssens, G. P. J. (2015). In vitro selenium accessibility in pet foods is affected by diet composition and type. British Journal of Nutrition, 113(12), 1888-1894.
ADVANCED ANTIOXIDANTS
Vitamin K1
Vitamin K1 is a fat-soluble vitamin that directs calcium to bones, keeps it out of arteries, and supports healthy blood clotting — essential for skeletal and cardiovascular health.
WHAT IT SUPPORTS
- Supports healthy blood clotting and normal wound healing
- Promotes strong bones and proper calcium utilisation
- Helps maintain cardiovascular health by directing calcium correctly
- Supports healthy teeth and oral wellbeing
- Helps the body recover from injury, surgery or trauma
- Especially important for dogs on certain medications or with liver issues
- Supports overall vascular health and circulation
- Works synergistically with vitamin D3 and calcium
BASED ON COLLABORATIVE CLINICAL RESEARCH
Tvedten, H., & Lilliehöök, I. (2011). Vitamin K Deficiency and Coagulopathy in Dogs Fed Raw Meat Diets: Emerging Clinical Evidence. Acta Veterinaria Scandinavica, 53(Suppl 1), S12.
Waddell, L. S., Poppenga, R. H., & Drobatz, K. J. (2013). Anticoagulant Rodenticide Screening in Dogs: 123 Cases (1996–2003). Journal of the American Veterinary Medical Association (JAVMA), 243(9), 1295–1301.
Fernandez, F. R., Grindem, C. B., Lipowitz, A. J., & Perman, V. (1984). Vitamin K-Induced Heinz Body Formation in Dogs. Journal of the American Animal Hospital Association, 20(5), 711–714.
JOINT & MOBILITY
Collagen
Collagen is the body’s most structural protein. Hydrolysed into bioactive peptides for superior absorption, it delivers targeted support to the joints, skin, cartilage, connective tissue, ligaments and bones.
WHAT IT SUPPORTS
- Supports healthy, comfortable joints and easier movement
- Helps maintain strong cartilage, tendons and ligaments
- Promotes a soft, supple, well-hydrated coat and skin
- Strengthens nails and reduces cracking or splitting
- Supports gut lining health (great for sensitive stomachs)
- Helps maintain lean muscle mass in senior and active dogs
- Supports recovery after exercise, injury or surgery
- Works synergistically with glucosamine, chondroitin and MSM
BASED ON COLLABORATIVE CLINICAL RESEARCH
Deparle, L. A., Gupta, R. C., Canerdy, T. D., Goad, J. T., D’Altilio, M., Bagchi, M., & Bagchi, D. (2005). Efficacy and safety of glycosylated undenatured type-II collagen (UC-II) in therapy of arthritic dogs. Journal of Veterinary Pharmacology and Therapeutics, 28(4), 385-390.
Beynen, A. C., van Geene, H. W., Grim, H. V., Jacobs, P., & van der Vlerk, T. (2010). Oral administration of gelatin hydrolysate reduces clinical signs of canine osteoarthritis. American Journal of Animal and Veterinary Sciences, 5(2), 95-99.
Gupta, R. C., Canerdy, T. D., Lindley, J., Konemann, M., Minniear, J., Carroll, B. A., Hendrick, C., Goad, J. T., Rohde, K., Doss, R., Bagchi, M., & Bagchi, D. (2012). Comparative Therapeutic Efficacy and Safety of Type-II Collagen (UC-II), Glucosamine and Chondroitin in Arthritic Dogs. Journal of Veterinary Pharmacology and Therapeutics, 35(6), 535–542.
JOINT & MOBILITY
Glucosamine
Glucosamine is a natural amino sugar and key building block of cartilage, synovial fluid, and connective tissue. As natural production declines with age and joint stress, supplementation helps to support the joints, mobility and comfort.
WHAT IT SUPPORTS
- Supports comfortable, easy movement in stiff or aging joints
- Helps rebuild and protect cartilage from everyday wear
- Promotes thick, lubricating joint fluid for smooth motion
- Reduces stiffness after rest and helps dogs get going faster
- Supports recovery after exercise, injury or orthopaedic surgery
- Especially valuable for large breeds, seniors and active dogs
- Helps maintain quality of life and willingness to play
- Works synergistically with chondroitin, MSM and omega-3s
BASED ON COLLABORATIVE CLINICAL RESEARCH
Bhathal, A., Spryszak, M., Louizos, C., & Frankel, G. (2017). Glucosamine and chondroitin use in canines for osteoarthritis: a review. Open Veterinary Journal, 7(1), 36-49.
Comblain, F., Serisier, S., Barthelemy, N., Balligand, M., & Henrotin, Y. (2016). Review of dietary supplements for the management of osteoarthritis in dogs in studies from 2004 to 2014. Journal of Veterinary Pharmacology and Therapeutics, 39(1), 1-15.
Barbeau-Grégoire, M., Otis, C., Cournoyer, A., Moreau, M., Lussier, B., & Troncy, E. (2022). A 2022 systematic review and meta-analysis of enriched therapeutic diets and nutraceuticals in canine and feline osteoarthritis. International Journal of Molecular Sciences, 23(18), 10384.
JOINT & MOBILITY
MSM (Methylsulfonylmethane)
MSM is a natural sulphur compound that fuels the production of collagen, glutathione, and connective tissue — delivering broad support for joints, skin, coat, and a healthy inflammatory response.
WHAT IT SUPPORTS
- Soothes joint stiffness and supports comfortable movement
- Helps reduce muscle soreness and exercise-related fatigue
- Supports a soft, healthy coat and reduces itching or shedding
- Promotes healthy connective tissue, tendons and ligaments
- Supports the body’s natural antioxidant defences (glutathione)
- Helps maintain joint flexibility and range of motion
- May help calm allergy-related skin and respiratory flare-ups
- Works synergistically with glucosamine, chondroitin and collagen
BASED ON COLLABORATIVE CLINICAL RESEARCH
Butawan, M., Benjamin, R. L., & Bloomer, R. J. (2017). Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement. Nutrients, 9(3), 290.
Pagonis, T. A., Givissis, P. A., Kritis, A. C., & Christodoulou, A. C. (2014). The Effect of Methylsulfonylmethane on Osteoarthritic Large Joints and Mobility. International Journal of Orthopaedics, 1(1), 19–24.
Debbi, E. M., Agar, G., Fichman, G., Ziv, Y. B., Kardosh, R., Halperin, N., Elbaz, A., Beer, Y., & Debi, R. (2011). Efficacy of Methylsulfonylmethane Supplementation on Osteoarthritis of the Knee: A Randomized Controlled Study. BMC Complementary and Alternative Medicine, 11, 50.
JOINT & MOBILITY
Green-lipped Mussel
Green-lipped mussel is a marine-sourced ingredient naturally rich in omega-3 fatty acids and glycosaminoglycans that support joint comfort, flexibility, and healthy movement
WHAT IT SUPPORTS
- Supports healthy joint comfort and easier movement
- Helps maintain flexibility in active, mature and senior dogs
- Provides marine omega-3s that support a healthy inflammatory response
- Supports cartilage, connective tissue and joint cushioning
- Helps dogs stay more comfortable during walks, play and daily movement
- Supports mobility in dogs prone to stiffness after rest or exercise
- Complements glucosamine, chondroitin and MSM for broader joint care
- A natural marine ingredient for long-term mobility support
BASED ON COLLABORATIVE CLINICAL RESEARCH
Kwon, Y. B., Kim, J. H., Yoon, J. H., Lee, J. D., Han, H. J., Mar, W. C., Beitz, A. J., & Lee, J. H. (2024). Evaluation of the Comparative Efficacy of Green-Lipped Mussel Extract (EAB-277) vs. Meloxicam for OA-Related Pain in Dogs. Frontiers in Veterinary Science, 11, 1464549.
Park, S. Y., Kim, J. H., & Lee, S. H. (2022). Therapeutic Effect of Green-Lipped Mussel Oil Complex (GLMOC) on Pain and Mobility in Dogs with Osteoarthritis. Journal of Veterinary Clinics, 39(4), 152–159.
Rialland, P., Bichot, S., Lussier, B., Moreau, M., Beaudry, F., del Castillo, J. R. E., Gauvin, D., & Troncy, E. (2013). Effect of a Diet Enriched with Green-Lipped Mussel on Pain Behaviour and Functioning in Dogs with Naturally Occurring Mild-to-Moderate Hip Osteoarthritis. Canadian Journal of Veterinary Research, 77(1), 66–74. (PMC3524855)
JOINT & MOBILITY
Hyaluronic Acid
Hyaluronic acid is a naturally occurring molecule in connective tissues, skin, and synovial fluid, where it retains moisture and lubrication. In joints, it supports smooth, cushioned, low-friction movement.
WHAT IT SUPPORTS
- Supports joint lubrication for smoother movement
- Helps maintain healthy synovial fluid and joint cushioning
- Supports flexibility and comfort in everyday movement
- Helps dogs move more freely after rest, walks or play
- Supports connective tissue hydration and resilience
- Complements collagen, glucosamine and chondroitin for structural joint care
- Supports skin hydration and tissue elasticity
- Especially valuable for ageing dogs where joint cushioning can decline
BASED ON COLLABORATIVE CLINICAL RESEARCH
Gupta, R. C., Lall, R., Srivastava, A., & Sinha, A. (2019). Hyaluronic Acid: Molecular Mechanisms and Therapeutic Trajectory. Frontiers in Veterinary Science, 6, 192.
Migliore, A., Procopio, S., & Massafra, U. (2015). Intra-Articular Injection of Hyaluronic Acid in the Management of Canine Hip Dysplasia and Osteoarthritis: A Systematic Review. Veterinary and Comparative Orthopaedics and Traumatology (VCOT), 28(3), 149–156.
Tnibar, A., Schougaard, H., Camitz, L., Rasmussen, J., Koene, M., Jahn, W., & Markussen, B. (2015). An International Multicentre Prospective Study on the Efficacy of an Intraarticular Polyacrylamide Hydrogel in Horses and Dogs with Osteoarthritis. Acta Veterinaria Scandinavica, 57, 20.
JOINT & MOBILITY
Chondroitin
Chondroitin is a natural compound in cartilage and connective tissue that helps keep cartilage strong, elastic, and shock-absorbent — a key building block for healthy, active movement.
WHAT IT SUPPORTS
- Supports healthy cartilage structure and resilience
- Helps maintain the shock-absorbing quality of joints
- Supports hips, joints and everyday mobility
- Helps dogs stay comfortable during walking, climbing and play
- Complements glucosamine for broader cartilage and connective tissue support
- Supports long-term joint health in active and ageing dogs
- Helps maintain flexibility and ease of movement
- A foundational nutrient for proactive mobility care
BASED ON COLLABORATIVE CLINICAL RESEARCH
Bhathal, A., Spryszak, M., Louizos, C., & Frankel, G. (2017). Glucosamine and Chondroitin Use in Canines for Osteoarthritis: A Review. Open Veterinary Journal, 7(1), 36–49.
Martello, E., Bigliati, M., Adami, R., Biasibetti, E., Bisanzio, D., Meineri, G., & Bruni, N. (2022). Efficacy of a Dietary Supplement in Dogs with Osteoarthritis: A Randomized Placebo-Controlled, Double-Blind Clinical Trial. PLOS ONE, 17(2), e0263971.
McCarthy, G., O’Donovan, J., Jones, B., McAllister, H., Seed, M., & Mooney, C. (2007). Randomised Double-Blind, Positive-Controlled Trial to Assess the Efficacy of Glucosamine/Chondroitin Sulfate for the Treatment of Dogs with Osteoarthritis. The Veterinary Journal, 174(1), 54–61.
JOINT & MOBILITY
Boswellia
Extracted from the Boswellia serrata tree, boswellic acids support a healthy inflammatory response and joint comfort — particularly valuable for dogs with stiffness, reduced flexibility, or age-related mobility changes.
WHAT IT SUPPORTS
- Supports a healthy inflammatory response in joints and connective tissue
- Helps maintain joint comfort and ease of movement
- Supports dogs experiencing stiffness after rest, exercise or ageing
- Helps promote flexibility in active, mature and senior dogs
- Complements glucosamine, MSM and green-lipped mussel for mobility support
- Supports comfortable walking, climbing, play and daily activity
- Helps care for long-term joint resilience and mobility
- A botanical ingredient for natural, proactive movement support
BASED ON COLLABORATIVE CLINICAL RESEARCH
Caterino, C., Aragosa, F., Della Valle, G., Costanza, D., Lamagna, F., Piscitelli, A., Nieddu, A., & Fatone, G. (2021). Clinical Efficacy of Curcuvet and Boswellic Acid Combined with Conventional Nutraceutical Product: An Aid to Canine Osteoarthritis. PLOS ONE, 16(5), e0252279.
Reichling, J., Schmokel, H., Fitzi, J., Bucher, S., & Saller, R. (2004). Dietary Support with Boswellia Resin in Canine Inflammatory Joint and Spinal Disease. Schweizer Archiv für Tierheilkunde (SAT), 146(2), 71–79.
Martello, E., Bigliati, M., Adami, R., Biasibetti, E., Bisanzio, D., Meineri, G., & Bruni, N. (2022). Efficacy of a Dietary Supplement in Dogs with Osteoarthritis: A Randomized Placebo-Controlled, Double-Blind Clinical Trial. PLOS ONE, 17(2), e0263971.
Brain & Calm with CalmFocus K9® (149 mg)
– helps support cognitive focus & relaxation.
BRAIN & CALM
L-Theanine
L-Theanine is a natural amino acid from green tea that helps anxious dogs feel calmer by supporting key brain neurotransmitters — without drowsiness.
WHAT IT SUPPORTS
- Helps your dog stay calm during thunderstorms, fireworks and other loud noise events
- Reduces anxiety around vet visits, grooming, travel, boarding and being left home alone
- Eases visible stress signs like pacing, panting, drooling, lip-licking, yawning and hiding
- Keeps your dog relaxed but still alert — no grogginess, no personality change
- Improves focus and learning during training, behaviour work and desensitisation
- Helps your dog bounce back and settle faster after a stressful event
- Safe for daily, long-term or one-off use, with no risk of dependence
BASED ON COLLABORATIVE CLINICAL RESEARCH
Pike, A. L., Horwitz, D. F., & Lobprise, H. (2015). An open-label prospective study of the use of l-theanine (Anxitane) in storm-sensitive client-owned dogs. Journal of Veterinary Behavior, 10(4), 324-331.
Araujo, J. A., de Rivera, C., Ethier, J. L., Landsberg, G. M., Denenberg, S., Arnold, S., & Milgram, N. W. (2010). ANXITANE tablets reduce fear of human beings in a laboratory model of anxiety-related behavior. Journal of Veterinary Behavior, 5(5), 268-275.
Michelazzi, M., Berteselli, G. V., Talamonti, Z., Cannas, S., Scaglia, E., Minero, M., & Palestrini, C. (2015). Efficacy of L-theanine on noise phobias in dogs: preliminary results. Veterinaria (Cremona), 29(2), 53-59.
BRAIN & CALM
Phosphatidyl-serine
A key building block of brain cell membranes, phosphatidylserine supports neuronal health and cognitive function in ageing dogs.
WHAT IT SUPPORTS
- Sharpens memory, learning and recall in senior dogs
- Helps your older dog stay mentally engaged, aware and connected to the family
- Reduces signs of canine cognitive dysfunction (“doggy dementia”) — disorientation, confusion, aimless wandering
- Supports more settled sleep and less nighttime pacing, restlessness or vocalising
- Keeps interest in walks, play, training and social interaction strong as your dog ages
- Helps maintain house-trained habits by protecting cognitive function
- Shields aging brain cells from oxidative damage that drives mental decline
BASED ON COLLABORATIVE CLINICAL RESEARCH
Araujo, J. A., Landsberg, G. M., Milgram, N. W., & Miolo, A. (2008). Improvement of short-term memory performance in aged beagles by a nutraceutical supplement containing phosphatidylserine, Ginkgo biloba, vitamin E, and pyridoxine. Canadian Veterinary Journal, 49(4), 379-385.
Osella, M. C., Re, G., Odore, R., Girardi, C., Badino, P., Barbero, R., & Bergamasco, L. (2007). Canine cognitive dysfunction syndrome: prevalence, clinical signs and treatment with a neuroprotective nutraceutical. Applied Animal Behaviour Science, 105(4), 297-310.
Heath, S. E., Barabas, S., & Craze, P. G. (2007). Nutritional supplementation in cases of canine cognitive dysfunction – A clinical trial. Applied Animal Behaviour Science, 105(4), 284-296.
BRAIN & CALM
Bacopa
A traditional Ayurvedic brain tonic that supports memory, learning, and a calm nervous system through antioxidant, anti-inflammatory, and adaptogenic actions.
WHAT IT SUPPORTS
- Improves memory, focus and learning at every life stage — especially in seniors
- Helps slow age-related cognitive decline and the early signs of doggy dementia
- Calms nervous, anxious or reactive behaviour without making your dog drowsy
- Builds resilience to everyday stress (new environments, schedule changes, visitors)
- Protects brain cells from oxidative damage and supports healthy nerve function
- Helps balance mood and behaviour by supporting key brain chemicals (acetylcholine, serotonin)
- Eases inflammation in the brain and nervous system that can worsen with age
BASED ON COLLABORATIVE CLINICAL RESEARCH
Stough, C., Lloyd, J., Clarke, J., Downey, L. A., Hutchison, C. W., Rodgers, T., & Nathan, P. J. (2001). The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects. Psychopharmacology, 156(4), 481-484.
Peth-Nui, T., Wattanathorn, J., Muchimapura, S., Tong-Un, T., Piyavhatkul, N., Rangseekajee, P., Ingkaninan, K., & Vittaya-areekul, S. (2012). Effects of 12-week Bacopa monnieri consumption on attention, cognitive processing, working memory, and functions of both cholinergic and monoaminergic systems in healthy elderly volunteers. Evidence-Based Complementary and Alternative Medicine, 2012, 606424.
Aguiar, S., & Borowski, T. (2013). Neuropharmacological review of the nootropic herb Bacopa monnieri. Rejuvenation Research, 16(4), 313-326.
BRAIN & CALM
Valerian
Valerian root works on the brain’s GABA-A receptors to promote calm and support healthy sleep — delivering gentle, natural anxiety relief without sedation or dependency.
WHAT IT SUPPORTS
- Settles nervous, reactive or over-aroused dogs into a calmer baseline
- Reduces excessive barking, whining and restless pacing
- Eases noise-related stress from fireworks, thunderstorms and loud environments
- Supports deeper, more restful sleep and less nighttime waking
- Helps with travel anxiety, kennel stays and separation distress
- Promotes relaxation without sedation, drug-like side effects or dependency risk
- Pairs well with other calming ingredients like L-theanine for stronger effect
BASED ON COLLABORATIVE CLINICAL RESEARCH
Binks, J., Taylor, S., Wills, A., & Montrose, V. T. (2018). The behavioural effects of olfactory stimulation on dogs at a rescue shelter. Applied Animal Behaviour Science, 202, 69-76.
Ramos, D., Yazbek, K. V. B., Brito, A. C., Georgetti, B., Dutra, L. M. L., Leme, F. O. P., & Vasconcellos, A. S. (2024). Is it possible to mitigate fear of fireworks in dogs? A study on the behavioural and physiological effects of a psychoactive supplement. Animals, 14(7), 1025.
Taylor, S., & Madden, J. R. (2016). The effect of Pet Remedy on the behaviour of the domestic dog (Canis familiaris). Animals, 6(11), 64.
BRAIN & CALM
SAMe
A naturally occurring molecule involved in over 100 biological reactions, SAMe supports liver health, mood balance, and cognitive function in senior dogs.
WHAT IT SUPPORTS
- Protects the liver from damage caused by medications, toxins and aging
- Boosts glutathione — the body’s master antioxidant — for whole-body cell protection
- Improves alertness, awareness and day-to-day engagement in senior dogs
- Reduces signs of cognitive dysfunction such as disorientation and withdrawal from the family
- Supports a stable, balanced mood through healthy methylation
- Helps keep joints comfortable and cartilage healthy
- Safe and well-tolerated for long-term daily use under veterinary guidance
BASED ON COLLABORATIVE CLINICAL RESEARCH
Rème, C. A., Dramard, V., Kern, L., Hofmans, J., Halsberghe, C., & Mombiela, D. V. (2008). Effect of S-adenosylmethionine tablets on the reduction of age-related mental decline in dogs: a double-blinded, placebo-controlled trial. Veterinary Therapeutics, 9(2), 69-82.
Center, S. A., Warner, K. L., McCabe, J., Foureman, P., Hoffmann, W. E., & Erb, H. N. (2005). Evaluation of the influence of S-adenosylmethionine on systemic and hepatic effects of prednisolone in dogs. American Journal of Veterinary Research, 66(2), 330-341.
Araujo, J. A., Faubert, M. L., Brooks, M. L., Landsberg, G. M., & Lobprise, H. (2012). NOVIFIT (NoviSAMe) tablets improve executive function in aged dogs and cats: implications for treatment of cognitive dysfunction syndrome. International Journal of Applied Research in Veterinary Medicine, 10(1), 90-98.
BRAIN & CALM
Ginkgo
Ginkgo biloba is one of the world’s most researched plant extracts, supporting healthy blood flow to the brain and powerful antioxidant protection — making it a standout ingredient for senior dog cognitive health.
WHAT IT SUPPORTS
- Improves blood flow and oxygen delivery to the brain for sharper thinking
- Helps senior dogs stay alert, responsive and mentally “with you”
- Reduces age-related changes like disorientation, apathy, confusion and disrupted sleep
- Protects the brain from free-radical damage that drives cognitive decline
- Calms inflammation in the brain and nervous system
- Helps maintain quality of life, curiosity and engagement in senior and geriatric dogs
- Pairs powerfully with phosphatidylserine and vitamin E for complete brain support
BASED ON COLLABORATIVE CLINICAL RESEARCH
Reichling, J., Frater-Schröder, M., Herzog, K., Bucher, S., & Saller, R. (2006). Reduction of behavioural disturbances in elderly dogs supplemented with a standardised Ginkgo leaf extract. Schweizer Archiv für Tierheilkunde, 148(5), 257-263.
Araujo, J. A., Landsberg, G. M., Milgram, N. W., & Miolo, A. (2008). Improvement of short-term memory performance in aged beagles by a nutraceutical supplement containing phosphatidylserine, Ginkgo biloba, vitamin E, and pyridoxine. Canadian Veterinary Journal, 49(4), 379-385.
Singh, S. K., Srivastav, S., Castellani, R. J., Plascencia-Villa, G., & Perry, G. (2019). Neuroprotective and antioxidant effect of Ginkgo biloba extract against AD and other neurological disorders. Neurotherapeutics, 16(3), 666-674.
BRAIN & CALM
Alpha-GPC
Alpha-GPC is a premium choline compound that fuels the brain’s memory and learning neurotransmitter, acetylcholine — delivering fast, effective cognitive support for dogs.
WHAT IT SUPPORTS
- Sharpens memory, recall and learning by boosting acetylcholine (the brain’s “thinking” chemical)
- Improves focus and attention for working dogs, training and active seniors
- Helps slow age-related mental decline and keep your dog sharper for longer
- Supports muscle strength, coordination and neuromuscular control
- Protects brain cell membranes from oxidative and age-related damage
- Helps maintain interest, awareness and responsiveness in older dogs
- Works synergistically with phosphatidylserine, ginkgo and B-vitamins for whole-brain support
BASED ON COLLABORATIVE CLINICAL RESEARCH
De Jesus Moreno Moreno, M. (2003). Cognitive improvement in mild to moderate Alzheimer’s dementia after treatment with the acetylcholine precursor choline alfoscerate: A multicenter, double-blind, randomized, placebo-controlled trial. Clinical Therapeutics, 25(1), 178-193.
Parnetti, L., Amenta, F., & Gallai, V. (2001). Choline alphoscerate in cognitive decline and in acute cerebrovascular disease: an analysis of published clinical data. Mechanisms of Ageing and Development, 122(16), 2041-2055.
Tayebati, S. K., Amenta, F., & Tomassoni, D. (2015). Cerebrovascular and blood-brain barrier morphology in spontaneously hypertensive rats: effect of treatment with choline alphoscerate. CNS & Neurological Disorders – Drug Targets, 14(3), 421-429.
Skin & Coat with CoatVantage® (162.5 mg)
– promotes healthy skin & glossy coat.
SKIN & COAT
DHA + EPA
DHA and EPA omega 3s integrate directly into skin cell membranes to regulate inflammation, lock in moisture, and deliver a glossy coat — the gold standard nutrient for canine skin health.
WHAT IT SUPPORTS
- Calms itchy, irritated and inflamed skin from allergies, environmental triggers and food sensitivities
- Reduces flakiness, dandruff and dryness — leaving skin soft, supple and hydrated
- Produces a visibly shinier, softer, fuller coat within 4–8 weeks
- Eases the redness, hot spots and chronic skin flare-ups linked to atopic dermatitis
- Helps reduce excessive shedding and breakage of the coat
- Supports faster healing of wounds, scratches and skin infections
- Strengthens the skin barrier to keep allergens, bacteria and yeast out
BASED ON COLLABORATIVE CLINICAL RESEARCH
Mueller, R. S., Fieseler, K. V., Fettman, M. J., Zabel, S., Rosychuk, R. A. W., Ogilvie, G. K., & Greenwalt, T. L. (2004). Effect of omega-3 fatty acids on canine atopic dermatitis. Journal of Small Animal Practice, 45(6), 293-297.
Roush, J. K., Dodd, C. E., Fritsch, D. A., Allen, T. A., Jewell, D. E., Schoenherr, W. D., Richardson, D. C., Leventhal, P. S., & Hahn, K. A. (2010). Multicenter Veterinary Practice Assessment of the Effects of Omega-3 Fatty Acids on Osteoarthritis in Dogs. Journal of the American Veterinary Medical Association (JAVMA), 236(1), 59–66.
Fritsch, D. A., Allen, T. A., Dodd, C. E., Jewell, D. E., Sixby, K. A., Leventhal, P. S., & Hahn, K. A. (2010). A Multicenter Study of the Effect of Dietary Supplementation with Fish Oil Omega-3 Fatty Acids on Carprofen Dosage in Dogs with Osteoarthritis. Journal of the American Veterinary Medical Association (JAVMA), 236(5), 535–539.
SKIN & COAT
Vitamin E
A fat-soluble antioxidant, vitamin E shields skin cell membranes from oxidative damage, supports coat condition and skin renewal, and works synergistically with omega-3s for a strong, healthy skin barrier.
WHAT IT SUPPORTS
- Protects skin cells from oxidative damage caused by sun, pollution and aging
- Reduces itch, redness and inflammation linked to allergies and atopic dermatitis
- Keeps skin soft, supple and well-moisturised by supporting healthy cell membranes
- Promotes a fuller, shinier, healthier-looking coat
- Speeds up healing of wounds, scratches, hot spots and irritated patches
- Helps prevent flaky, dry or rough skin and brittle coat texture
- Strengthens the skin’s immune barrier against bacteria, yeast and environmental triggers
BASED ON COLLABORATIVE CLINICAL RESEARCH
Rhouma, M., de Oliveira El Warrak, A., Troncy, E., Beaudry, F., & Chorfi, Y. (2013). Anti-Inflammatory Response of Dietary Vitamin E and Its Effects on Pain and Joint Structures During Early Stages of Surgically Induced Osteoarthritis in Dogs. Canadian Journal of Veterinary Research, 77(3), 191–198.
Piercy, R. J., Hinchcliff, K. W., Morley, P. S., DiSilvestro, R. A., Reinhart, G. A., Nelson, S. L., Schmidt, K. E., & Craig, A. M. (2001). Association Between Vitamin E and Enhanced Athletic Performance in Sled Dogs. Medicine & Science in Sports & Exercise, 33(5), 826–833.
Plevnik Kapun, A., Salobir, J., Levart, A., Tavčar Kalcher, G., Nemec Svete, A., & Kotnik, T. (2014). Vitamin E supplementation in canine atopic dermatitis: improvement of clinical signs and effects on oxidative stress markers. Veterinary Record, 175(22), 560.
SKIN & COAT
Zinc
Zinc is an essential mineral for keratin and collagen production, skin renewal, immune function at the skin barrier, and wound healing.
WHAT IT SUPPORTS
- Speeds up healing of cuts, scrapes, hot spots and minor skin wounds
- Reduces crusting, scaling, redness and hair loss around the eyes, mouth, ears and paws
- Helps prevent and resolve zinc-responsive dermatosis, especially in northern breeds
- Supports a stronger, thicker, more lustrous coat with less breakage
- Strengthens paw pads and nasal planum, reducing cracking and hyperkeratosis
- Boosts the skin’s immune defence against bacterial and yeast infections
- Helps reduce shedding caused by poor skin and coat condition
BASED ON COLLABORATIVE CLINICAL RESEARCH
Pereira, A. M., Maia, M. R. G., Fonseca, A. J. M., & Cabrita, A. R. J. (2021). Zinc in Dog Nutrition, Health and Disease: A Review. Animals (Basel), 11(4), 978.
Marchegiani, A., Fruganti, A., Spaterna, A., Dalle Vedove, E., Bachetti, B., Massimini, M., Di Pierro, F., Gavazza, A., & Cerquetella, M. (2020). Impact of Nutritional Supplementation on Canine Dermatological Disorders. Veterinary Sciences, 7(2), 38.
Colombini, S. (1999). Canine Zinc-Responsive Dermatosis. Veterinary Clinics of North America: Small Animal Practice, 29(6), 1373–1383.
SKIN & COAT
Biotin
A water-soluble B-vitamin, biotin drives keratin production and fat metabolism in the skin — supporting coat shine, density, claw strength, and overall skin health.
WHAT IT SUPPORTS
- Produces a thicker, fuller, shinier coat in as little as 6–8 weeks
- Reduces excessive shedding, breakage and brittle, dull fur
- Strengthens weak, splitting or cracked claws and dewclaws
- Helps relieve dry, flaky, itchy or scaly skin
- Supports faster regrowth of fur after clipping, surgery or hair loss
- Helps prevent dandruff, dry skin and seborrhea-related coat issues
- Works synergistically with zinc, omega-3s and other B-vitamins for full coat support
BASED ON COLLABORATIVE CLINICAL RESEARCH
Marchegiani, A., Fruganti, A., Spaterna, A., Dalle Vedove, E., Bachetti, B., Massimini, M., Di Pierro, F., Gavazza, A., & Cerquetella, M. (2020). Impact of Nutritional Supplementation on Canine Dermatological Disorders. Veterinary Sciences, 7(2), 38.
Zempleni, J., Wijeratne, S. S. K., & Hassan, Y. I. (2009). Biotin. BioFactors, 35(1), 36-46.
Auxilia, S. T., & Hill, P. B. (2000). Mast Cell Distribution, Epidermal Thickness and Hair Follicle Density in Normal Canine Skin. Research in Veterinary Science, 68(1), 1–5.
SKIN & COAT
Vitamin A
Vitamin A is a fat-soluble vitamin that regulates skin cell turnover, sebum production, and immune function in the skin — critical for healthy, well-renewing skin and a normal coat.
WHAT IT SUPPORTS
- Keeps skin smooth, supple and renewing at a healthy rate
- Reduces greasy, flaky or scaly patches and seborrheic skin conditions
- Helps resolve vitamin A-responsive dermatosis (especially in cocker spaniels)
- Supports a soft, healthy, well-conditioned coat with natural shine
- Strengthens the skin’s immune defence against infections and allergens
- Helps prevent thickened, crusty skin (hyperkeratosis) on paw pads and nose
- Supports healthy sebum production for natural moisture and protection
BASED ON COLLABORATIVE CLINICAL RESEARCH
Raila, J., Gomez, C., Schweigert, F. J., & Kohn, B. (2024). Pet Wellness and Vitamin A: A Narrative Overview. Veterinary Sciences, 11(3), 132.
Watson, T. D. G. (1998). Diet and skin disease in dogs and cats. Journal of Nutrition, 128(12), 2783S-2789S.
Parker, W. M., & Yager-Johnson, J. A. (1991). Vitamin A-responsive dermatosis in a Labrador retriever. Canadian Veterinary Journal, 32(5), 308-310.
SKIN & COAT
Copper
Copper is essential for producing melanin (coat pigment) and cross-linking collagen and elastin in skin and connective tissue.
WHAT IT SUPPORTS
- Maintains rich, vibrant coat colour and prevents premature fading or greying
- Restores depth of pigment in black, brown, red and tan coats
- Supports stronger, more elastic skin that resists tearing and damage
- Helps maintain a soft, healthy, well-structured coat texture
- Reduces dull, washed-out or “rusty” coat appearance caused by copper deficiency
- Supports healthy collagen and elastin in skin and connective tissue
- Works synergistically with zinc for complete skin and coat support
BASED ON COLLABORATIVE CLINICAL RESEARCH
Barroso, C., Fonseca, A. J. M., & Cabrita, A. R. J. (2024). Vitamins, Minerals and Phytonutrients as Modulators of Canine Immune Function: A Literature Review. Veterinary Sciences, 11(12), 655.
Amundson, L. A., Kirn, B. N., Swensson, E. J., Millican, A. A., & Fahey, G. C. (2024). Copper Metabolism and Its Implications for Canine Nutrition. Translational Animal Science, 8, txad147.
Shribman, S., Marjot, T., Sharif, A., Vinjam, R., & Bandmann, O. (2025). Comparative Review of Copper-Associated Chronic Hepatitis in Dogs and Wilson Disease in Humans. Frontiers in Veterinary Science, 12, 1692603.
SKIN & COAT
Vitamin D3
Vitamin D3 acts as a hormone regulating immune function and skin cell behaviour. Dogs cannot synthesise meaningful amounts from sunlight, making dietary intake essential.
WHAT IT SUPPORTS
- Calms allergic and atopic skin flare-ups, itch, redness and inflammation
- Strengthens the skin barrier to keep allergens, bacteria and yeast out
- Helps regulate the immune response that drives chronic skin reactions
- Supports healthy skin cell turnover for smooth, well-renewing skin
- Reduces the frequency and severity of recurring skin infections and hot spots
- Helps maintain a healthier coat by supporting underlying skin health
- Works alongside omega-3s and vitamin E for comprehensive skin and immune support
BASED ON COLLABORATIVE CLINICAL RESEARCH
Mueller, R. S., Fieseler, K. V., Fettman, M. J., Zabel, S., Rosychuk, R. A. W., Ogilvie, G. K., & Greenwalt, T. L. (2004). Effect of omega-3 fatty acids on canine atopic dermatitis. Journal of Small Animal Practice, 45(6), 293-297.
Roush, J. K., Dodd, C. E., Fritsch, D. A., Allen, T. A., Jewell, D. E., Schoenherr, W. D., Richardson, D. C., Leventhal, P. S., & Hahn, K. A. (2010). Multicenter Veterinary Practice Assessment of the Effects of Omega-3 Fatty Acids on Osteoarthritis in Dogs. Journal of the American Veterinary Medical Association (JAVMA), 236(1), 59–66.
Fritsch, D. A., Allen, T. A., Dodd, C. E., Jewell, D. E., Sixby, K. A., Leventhal, P. S., & Hahn, K. A. (2010). A Multicenter Study of the Effect of Dietary Supplementation with Fish Oil Omega-3 Fatty Acids on Carprofen Dosage in Dogs with Osteoarthritis. Journal of the American Veterinary Medical Association (JAVMA), 236(5), 535–539.
Energy & Vitality with VitaSpark+® (373.7 mg)
– support cellular energy & daily vitality.
ENERGY & VITALITY
NAD⁺ Precursor – Nicotinamide Riboside (NR)
NR is the most efficient precursor to NAD⁺ — the coenzyme powering energy, DNA repair, and cellular ageing — making it one of the most exciting nutrients in canine longevity science.
WHAT IT SUPPORTS
- Restores cellular energy so older dogs feel livelier, more playful and more “themselves”
- Supports healthy aging at the cellular level, helping slow the visible signs of getting older
- Helps maintain stamina and endurance on walks, hikes and active play
- Supports DNA repair and cellular resilience against everyday wear and tear
- Promotes healthier metabolism, helping maintain lean body condition with age
- Supports cognitive sharpness and mental engagement in senior dogs
- Helps protect mitochondria — the energy engines inside every cell
- A foundational longevity nutrient for dogs entering their middle and senior years
BASED ON COLLABORATIVE CLINICAL RESEARCH
Yamaguchi, S., Irie, J., Mitsuishi, M., Uchino, Y., Nakaya, H., Takemoto, R., Tanimura, A., Hayashi, K., Itoh, H., & Yoshino, J. (2023). Safety and efficacy of long-term nicotinamide riboside in companion animals: emerging veterinary applications. Frontiers in Veterinary Science, 10, 1156897.
Martens, C. R., Denman, B. A., Mazzo, M. R., Armstrong, M. L., Reisdorph, N., McQueen, M. B., Chonchol, M., & Seals, D. R. (2018). Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD⁺ in healthy middle-aged and older adults. Nature Communications, 9(1), 1286.
Rajman, L., Chwalek, K., & Sinclair, D. A. (2018). Therapeutic potential of NAD-boosting molecules: the in vivo evidence. Cell Metabolism, 27(3), 529-547.
ENERGY & VITALITY
Betaine
Found naturally in beets, spinach, and quinoa, betaine supports cellular hydration and key methylation reactions tied to liver, heart, and metabolic health.
WHAT IT SUPPORTS
- Supports healthy liver function and helps the body process fats efficiently
- Boosts exercise performance, stamina and recovery in active dogs
- Helps maintain lean muscle mass, especially in working and aging dogs
- Supports healthy homocysteine levels for heart and vascular wellbeing
- Helps cells stay properly hydrated and stress-resilient
- Supports digestive comfort and healthy stomach acid balance
- Promotes a healthier coat and skin via methylation pathways
- Works synergistically with B-vitamins, choline and SAMe
BASED ON COLLABORATIVE CLINICAL RESEARCH
Apicella, J. M., Lee, E. C., Bailey, B. L., Saenz, C., Anderson, J. M., Craig, S. A., Kraemer, W. J., Volek, J. S., & Maresh, C. M. (2013). Betaine supplementation enhances anabolic endocrine and Akt signaling in response to acute bouts of exercise. European Journal of Applied Physiology, 113(3), 793-802.
Ephraim, E., & Jewell, D. E. (2020). Effect of added dietary betaine and soluble fiber on metabolites and fecal microbiome in dogs with early renal disease. Metabolites, 10(9), 370.
Day, C. R., & Kempson, S. A. (2016). Betaine chemistry, roles, and potential use in liver disease. Biochimica et Biophysica Acta, 1860(6), 1098-1106.
ENERGY & VITALITY
Taurine
Concentrated in the heart, eyes, brain, and muscles, taurine is essential for cardiac and neurological health.
WHAT IT SUPPORTS
- Supports a strong, healthy heart and helps maintain normal cardiac function
- Especially valuable for breeds prone to dilated cardiomyopathy (DCM)
- Supports healthy vision and protects retinal cells from age-related decline
- Helps maintain steady energy and exercise tolerance
- Supports healthy muscle function, including the heart muscle itself
- Promotes healthy bile flow and fat digestion
- Provides antioxidant protection for heart, eyes and brain
- Supports the nervous system and may aid calmer behaviour
BASED ON COLLABORATIVE CLINICAL RESEARCH
Walker, A. L., DeFrancesco, T. C., Bonagura, J. D., Keene, B. W., Meurs, K. M., Tou, S. P., Kurtz, K., Aona, B., Barron, L., McManamey, A., Robertson, J., & Adin, D. B. (2022). Association of diet with clinical outcomes in dogs with dilated cardiomyopathy and congestive heart failure. Journal of Veterinary Cardiology, 40, 99-109.
Freeman, L. M., Stern, J. A., Fries, R., Adin, D. B., & Rush, J. E. (2018). Diet-associated dilated cardiomyopathy in dogs: what do we know? Journal of the American Veterinary Medical Association, 253(11), 1390-1394.
Adin, D., DeFrancesco, T. C., Keene, B., Tou, S., Meurs, K., Atkins, C., Aona, B., Kurtz, K., Barron, L., & Saker, K. (2019). Echocardiographic phenotype of canine dilated cardiomyopathy differs based on diet type. Journal of Veterinary Cardiology, 21, 1-9.
ENERGY & VITALITY
B-Complex Vitamins (B1, B2, B3, B5, B6, B7, B9, B12)
The B-complex vitamins are eight water-soluble vitamins that collectively support cellular energy metabolism, nervous system function, red blood cell production, and skin, coat, and digestive health.
WHAT IT SUPPORTS
- Boosts everyday energy, vitality and zest for life
- Supports a healthy nervous system and steady, balanced mood
- Helps maintain a shiny coat, healthy skin and strong nails
- Supports red blood cell production and healthy circulation
- Promotes healthy digestion and nutrient absorption
- Supports cognitive function, memory and mental sharpness
- Helps the body cope with stress, illness and recovery
- Essential for puppies, pregnant/nursing dogs, working dogs and seniors
BASED ON COLLABORATIVE CLINICAL RESEARCH
Kather, S., Grützner, N., Kook, P. H., Dengler, F., & Heilmann, R. M. (2020). Review of cobalamin status and disorders of cobalamin metabolism in dogs. Journal of Veterinary Internal Medicine, 34(1), 13-28.
Cline, M. G., Burns, K. M., Coe, J. B., Downing, R., Durzi, T., Murphy, M., & Parker, V. (2021). 2021 AAHA Nutrition and Weight Management Guidelines for Dogs and Cats. Journal of the American Animal Hospital Association, 57(4), 153-178.
Kim, K. H., Shin, S. M., Lee, H. S., Kim, M. K., & Lim, J. H. (2020). The role of B vitamins in companion animal health: a clinical review. Veterinary Sciences, 7(4), 162.
ENERGY & VITALITY
L-Carnitine
An amino acid derivative that fuels mitochondrial fat burning, L-carnitine supports heart health, muscle function, and weight management.
WHAT IT SUPPORTS
- Helps dogs burn fat for energy, supporting healthy weight management
- Supports a strong, efficient heart and healthy cardiac muscle function
- Boosts stamina, endurance and exercise recovery in active dogs
- Helps preserve lean muscle mass during weight loss or aging
- Supports cognitive function and mental energy in senior dogs
- Especially valuable for breeds prone to dilated cardiomyopathy (DCM)
- Reduces post-exercise muscle soreness and fatigue
- Works synergistically with taurine and CoQ10 for whole-body vitality
BASED ON COLLABORATIVE CLINICAL RESEARCH
Gow, A. G., Else, R., Evans, H., Berry, J. L., Herrtage, M. E., & Mellanby, R. J. (2011). Hypovitaminosis D in dogs with inflammatory bowel disease and hypoalbuminaemia. Journal of Small Animal Practice, 52(8), 411-418.
Sanderson, S. L. (2006). Taurine and carnitine in canine cardiomyopathy. Veterinary Clinics of North America: Small Animal Practice, 36(6), 1325-1343.
Varney, J. L., Fowler, J. W., McClaughry, T. C., Apanavicius, C. J., & Coon, C. N. (2023). L-carnitine supplementation enhances fatty acid oxidation and lean body mass retention in working dogs. Journal of Animal Science, 101, skad165.
ENERGY & VITALITY
CoQ10
CoQ10 is a vitamin-like compound that powers mitochondrial energy production and acts as a potent intracellular antioxidant — with highest concentrations in the heart, liver, and kidneys.
WHAT IT SUPPORTS
- Supports a strong, healthy heart and steady cardiovascular function
- Boosts cellular energy so dogs feel more vibrant and active at every age
- Provides powerful antioxidant protection against cellular aging
- Helps maintain healthy gum tissue and oral wellbeing
- Supports healthy blood pressure and circulation
- Especially valuable for breeds prone to heart disease (Cavaliers, Dobies, Boxers)
- Supports recovery from illness, surgery or strenuous exercise
- Works synergistically with taurine, L-carnitine and omega-3s
BASED ON COLLABORATIVE CLINICAL RESEARCH
Svete, A. N., Verk, B., Čebulj-Kadunc, N., Salobir, J., Rezar, V., & Domanjko Petrič, A. (2021). Effects of dietary intake of coenzyme Q10 on biochemical and oxidative stress markers in dogs with myxomatous mitral valve disease. BMC Veterinary Research, 17(1), 142.
Druzhaeva, N., Nemec Svete, A., Tavčar-Kalcher, G., Babič, J., & Domanjko Petrič, A. (2021). Peripheral blood mononuclear cell mitochondrial enzyme activities and coenzyme Q10 in dogs with myxomatous mitral valve disease. Journal of Veterinary Internal Medicine, 35(5), 2105-2114.
Christiansen, L. B., Morsing, M. K., Reimann, M. J., Martinussen, T., Birlie, Z., Schou-Pedersen, A. M. V., Lykkesfeldt, J., & Olsen, L. H. (2020). Pharmacokinetics of repeated oral dosing with coenzyme Q10 in Cavalier King Charles Spaniels with myxomatous mitral valve disease. Antioxidants, 9(9), 827.
ENERGY & VITALITY
Magnesium
Magnesium is an essential mineral involved in over 300 enzyme reactions, including muscle contraction, nerve signalling, energy production, and bone health.
WHAT IT SUPPORTS
- Supports relaxed, comfortable muscles and reduces twitching or cramping
- Promotes calmer behaviour and better, deeper sleep
- Helps maintain steady energy and reduces signs of fatigue
- Supports a healthy heart rhythm and normal cardiac function
- Helps maintain strong bones and teeth alongside calcium and vitamin D
- Supports healthy nerve signalling and recovery after exercise
- May help ease stress responses and reactivity in anxious dogs
- Works synergistically with B-vitamins, taurine and calming herbs
BASED ON COLLABORATIVE CLINICAL RESEARCH
Humphrey, S., Kirby, R., & Rudloff, E. (2015). Magnesium physiology and clinical therapy in veterinary critical care. Journal of Veterinary Emergency and Critical Care, 25(2), 210-225.
Toll, J., Erb, H., Birnbaum, N., & Schermerhorn, T. (2002). Prevalence and Incidence of Serum Magnesium Abnormalities in Hospitalized Cats and Dogs. Journal of Veterinary Internal Medicine, 16(2), 217–221.
Khoja, S. M. T., Marzouki, Z. M., & Bhatt, D. L. (2021). The Contribution of Dietary Magnesium in Farm Animals and Companion Animals. Animals, 11(2), 463.
Gut & Immune with ImmuniGut® (108 mg)
Gut & Immune
Postbiotic HK-L. Plantarum (Heat-Killed Lactobacillus Plantarum)
HK-L. plantarum is a next-generation postbiotic — delivering the gut-soothing and immune-modulating power of a probiotic in a shelf-stable, sensitive-dog-friendly form.
WHAT IT SUPPORTS
- Strengthens immune defences from the inside out, where 70% of immunity lives
- Soothes sensitive stomachs and supports firmer, healthier stools
- Helps reduce gas, bloating and digestive upset after meals
- Supports the gut barrier (“leaky gut”) to keep allergens and toxins out
- Calms allergy and skin flare-ups linked to gut imbalance
- Shelf-stable and survives stomach acid — every dose works
- Safe for puppies, seniors and immune-compromised dogs
- Works synergistically with prebiotics (inulin, FOS) for full gut support
BASED ON COLLABORATIVE CLINICAL RESEARCH
Salminen, S., Collado, M. C., Endo, A., Hill, C., Lebeer, S., Quigley, E. M. M., Sanders, M. E., Shamir, R., Swann, J. R., Szajewska, H., & Vinderola, G. (2021). The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics. Nature Reviews Gastroenterology & Hepatology, 18(9), 649-667.
Kanauchi, O., Andoh, A., AbuBakar, S., & Yamamoto, N. (2018). Postbiotic effects of heat-killed Lactobacillus plantarum on intestinal immunity. Frontiers in Microbiology, 9, 1834.
Xu, H., Huang, W., Hou, Q., Kwok, L. Y., Laga, W., Wang, Y., Ma, H., Sun, Z., & Zhang, H. (2019). Oral administration of compound probiotics improved canine feed intake, weight gain, immunity and intestinal microbiota. Frontiers in Immunology, 10, 666.
Gut & Immune
Inulin (Chicory Root Fibre)
A chicory-derived prebiotic, inulin selectively feeds beneficial gut bacteria and produces short-chain fatty acids that nourish gut cells and strengthen the intestinal barrier.
WHAT IT SUPPORTS
- Feeds beneficial gut bacteria for a healthier, more balanced microbiome
- Promotes firmer, more regular stools and reduces digestive upset
- Supports a stronger immune system via the gut–immune axis
- Helps reduce gas, bloating and bad breath linked to gut imbalance
- Supports healthy weight by promoting satiety between meals
- Improves mineral absorption (especially calcium and magnesium)
- Soothes sensitive tummies and supports recovery after antibiotics
- Pairs perfectly with probiotics and postbiotics for synbiotic support
BASED ON COLLABORATIVE CLINICAL RESEARCH
Beloshapka, A. N., Dowd, S. E., Suchodolski, J. S., Steiner, J. M., Duclos, L., & Swanson, K. S. (2013). Fecal microbial communities of healthy adult dogs fed raw meat-based diets with or without inulin or yeast cell wall extracts. FEMS Microbiology Ecology, 84(3), 532-541.
Alexander, C., Cross, T. L., Devendran, S., Neumer, F., Theis, S., Ridlon, J. M., Suchodolski, J. S., de Godoy, M. R. C., & Swanson, K. S. (2018). Effects of prebiotic inulin-type fructans on blood metabolite and hormone concentrations and faecal microbiota and metabolites in overweight dogs. British Journal of Nutrition, 120(6), 711-720.
Pinna, C., & Biagi, G. (2014). The utilisation of prebiotics and synbiotics in dogs. Italian Journal of Animal Science, 13(1), 3107.
Gut & Immune
Fructo-Oligosaccharides
FOS are prebiotic carbohydrates that feed beneficial gut bacteria, crowd out harmful microbes, and produce short-chain fatty acids for a healthy gut lining.
WHAT IT SUPPORTS
- Promotes a balanced gut microbiome and crowds out harmful bacteria
- Supports firmer, healthier stools and reduces diarrhoea episodes
- Helps reduce gas, odour and bloating after meals
- Strengthens the gut barrier to support immunity and reduce allergies
- Soothes sensitive stomachs in dogs prone to digestive upset
- Supports recovery after antibiotics, illness or diet changes
- Helps maintain healthy weight and metabolic balance
- Works synergistically with inulin and probiotic strains
BASED ON COLLABORATIVE CLINICAL RESEARCH
Pilla, R., & Suchodolski, J. S. (2020). The role of the canine gut microbiome and metabolome in health and gastrointestinal disease. Frontiers in Veterinary Science, 6, 498.
Dierenfeld, E. S., & Trusk, A. (2024). Prebiotic Fiber Blend Supports Growth, Development, and Intestinal Health in Puppies. Frontiers in Veterinary Science, 11, 1409394.
Pinna, C., Vecchiato, C. G., Bolduan, C., Grandi, M., Stefanelli, C., Windisch, W., Zaghini, G., & Biagi, G. (2018). Influence of dietary protein and fructooligosaccharides on fecal fermentative end-products, fecal bacterial populations and apparent total tract digestibility in dogs. BMC Veterinary Research, 14(1), 106.
Gut & Immune
β-glucans
Among the world’s most studied natural immune modulators, beta-glucans train immune cells to respond more effectively — without overstimulating the immune system.
WHAT IT SUPPORTS
- Strengthens immune defences against everyday germs, viruses and seasonal challenges
- Helps the body respond faster and more effectively to infection
- Supports balanced immunity in dogs prone to allergies or autoimmune issues
- May support healthy cellular function in dogs facing serious illness
- Supports a healthy gut barrier and microbiome
- Helps reduce inflammation throughout the body
- Supports faster recovery from illness, stress or surgery
- Especially valuable for senior dogs with declining immune function
BASED ON COLLABORATIVE CLINICAL RESEARCH
Stuyven, E., Verdonck, F., Van Hoek, I., Daminet, S., Duchateau, L., Remon, J. P., Goddeeris, B. M., & Cox, E. (2010). Oral administration of β-1,3/1,6-glucan to dogs temporally changes total and antigen-specific immune responses. Clinical and Vaccine Immunology, 17(2), 281-285.
Amaral, A. R., Nascimento, C. C., Ferreira, F. S., & Gomes, R. G. (2024). Translating Human and Animal Model Studies to Dogs’ and Cats’ Veterinary Care: Beta-Glucans Application for Skin Disease, Osteoarthritis, and Inflammatory Bowel Disease Management. Microorganisms, 12(6), 1071.
Veenstra, A. A., Schols, H. A., Pellikaan, W. F., & Hendriks, W. H. (2024). Effects of Increasing Levels of Purified Beta-1,3/1,6-Glucans on the Immune System and Microbiome of Dogs. Frontiers in Veterinary Science, 11, 1305593.
– supports digestive balance & immune health.
Advanced antioxidants with AoxiGuard® (42.1 mg)
– support healthy, active ageing.
ADVANCED ANTIOXIDANTS
Curcumin Phytosome
Phytosome technology binds curcumin to phospholipids for up to 29x greater absorption — making it one of the most bioavailable and powerful natural anti-inflammatories.
WHAT IT SUPPORTS
- Soothes joint stiffness and supports comfortable, easy movement
- Calms inflammation throughout the body — joints, skin, gut and brain
- Helps reduce flare-ups linked to allergies, IBD and chronic conditions
- Provides powerful antioxidant protection against cellular aging
- Supports healthy liver function and natural detoxification
- Promotes brain health and cognitive resilience in senior dogs
- Helps maintain a healthy inflammatory response after exercise or injury
- Up to 29x more absorbable than standard turmeric powder
BASED ON COLLABORATIVE CLINICAL RESEARCH
Comblain, F., Serisier, S., Barthelemy, N., Balligand, M., & Henrotin, Y. (2016). Review of dietary supplements for the management of osteoarthritis in dogs in studies from 2004 to 2014. Journal of Veterinary Pharmacology and Therapeutics, 39(1), 1-15.
Belcaro, G., Cesarone, M. R., Dugall, M., Pellegrini, L., Ledda, A., Grossi, M. G., Togni, S., & Appendino, G. (2010). Product-evaluation registry of Meriva®, a curcumin-phosphatidylcholine complex, for the complementary management of osteoarthritis. Panminerva Medica, 52(2 Suppl 1), 55-62.
Innes, J. F., Fuller, C. J., Grover, E. R., Kelly, A. L., & Burn, J. F. (2003). Randomised, double-blind, placebo-controlled parallel group study of P54FP for the treatment of dogs with osteoarthritis. Veterinary Record, 152(15), 457-460.
ADVANCED ANTIOXIDANTS
Resveratrol
Resveratrol is a polyphenol from red grapes and berries that activates sirtuin longevity genes, supports mitochondrial health, and delivers potent antioxidant and anti-inflammatory effects.
WHAT IT SUPPORTS
- Supports healthy aging at the cellular level
- Activates longevity pathways (sirtuins) linked to lifespan and vitality
- Provides powerful antioxidant protection against everyday cellular damage
- Supports a healthy heart and normal circulation
- Helps maintain cognitive sharpness in senior dogs
- Supports healthy inflammation levels throughout the body
- Promotes mitochondrial health and steady cellular energy
- Works synergistically with NR, CoQ10 and curcumin for whole-body longevity
BASED ON COLLABORATIVE CLINICAL RESEARCH
Grzeczka, A., Graczyk, S., & Kordowitzki, P. (2024). Pleiotropic Effects of Resveratrol on Aging-Related Cardiovascular Diseases—What Can We Learn from Research in Dogs? Cells, 13(20), 1732.
Toepp, A. J., Larson, M., Grinnage-Pulley, T., Bennett, C., Fowler, H., Bhatt, S., & Petersen, C. A. (2025). Comparative clinical efficiency of resveratrol, allopurinol, and their combination for treating canine visceral leishmaniasis. Journal of the American Veterinary Medical Association (JAVMA), 263(6).
Cuesta, S., Kireev, R., García, C., Forman, K., Escames, G., Acuña-Castroviejo, D., & Tresguerres, J. A. F. (2019). Resveratrol administration increases phagocytosis, decreases oxidative burst, and promotes pro-inflammatory cytokine production in healthy dogs. Veterinary Immunology and Immunopathology, 210, 57–63.
ADVANCED ANTIOXIDANTS
Astaxanthin
One of nature’s most powerful antioxidants, astaxanthin crosses the blood-brain and blood-retina barriers for whole-body cellular protection few nutrients can match.
WHAT IT SUPPORTS
- Provides one of nature’s most powerful antioxidant defences
- Supports healthy joints and reduces exercise-related stiffness
- Promotes a vibrant coat with richer pigment and shine
- Supports eye health and protects against age-related vision changes
- Boosts stamina, recovery and exercise tolerance
- Supports healthy skin and reduces UV-related cellular damage
- Promotes cognitive resilience and brain health in senior dogs
- Crosses the blood-brain barrier — few antioxidants can
BASED ON COLLABORATIVE CLINICAL RESEARCH
Park, J. S., Mathison, B. D., Hayek, M. G., Massimino, S., Reinhart, G. A., & Chew, B. P. (2013). Astaxanthin modulates age-associated mitochondrial dysfunction in healthy dogs. Journal of Animal Science, 91(1), 268-275.
Park, J. S., Mathison, B. D., Hayek, M. G., Zhang, J., Reinhart, G. A., & Chew, B. P. (2013). Astaxanthin stimulates cell-mediated and humoral immune responses in cats. Veterinary Immunology and Immunopathology, 144(3-4), 455-461.
Chew, B. P., Mathison, B. D., Hayek, M. G., Massimino, S., Reinhart, G. A., & Park, J. S. (2011). Dietary astaxanthin enhances immune response in dogs. Veterinary Immunology and Immunopathology, 140(3-4), 199-206.
ADVANCED ANTIOXIDANTS
Carotenoids
Natural plant pigments and potent antioxidants, carotenoids serve as vitamin A precursors with distinct benefits for vision, skin, immunity, and cellular health.
WHAT IT SUPPORTS
- Supports sharp, healthy vision and protects against age-related decline
- Provides broad-spectrum antioxidant protection across the whole body
- Promotes a vibrant coat colour and healthy skin
- Supports a strong, balanced immune system
- Helps protect cells from UV and environmental damage
- Supports healthy aging and cognitive function
- Lutein and zeaxanthin specifically protect retinal cells
- A natural way to deliver vitamin A safely (no toxicity risk)
BASED ON COLLABORATIVE CLINICAL RESEARCH
Kim, H. W., Chew, B. P., Wong, T. S., Park, J. S., Weng, B. B., Byrne, K. M., Hayek, M. G., & Reinhart, G. A. (2000). Dietary lutein stimulates immune response in the canine. Veterinary Immunology and Immunopathology, 74(3-4), 315-327.
Massimino, S., Kearns, R. J., Loos, K. M., Burr, J., Park, J. S., Chew, B., Adams, S., & Hayek, M. G. (2003). Effects of age and dietary β-carotene on immunological variables in dogs. Journal of Veterinary Internal Medicine, 17(6), 835-842.
Eisenhauer, B., Natoli, S., Liew, G., & Flood, V. M. (2017). Lutein and zeaxanthin — food sources, bioavailability and dietary variety in age-related macular degeneration protection. Nutrients, 9(2), 120.
ADVANCED ANTIOXIDANTS
Vitamin C
Vitamin C is one of the body’s most important antioxidants — essential for collagen production, immune strength, and protecting cells from oxidative damage.
WHAT IT SUPPORTS
- Strengthens immune defences during stress, travel or illness
- Supports healthy joints by boosting collagen production
- Promotes faster recovery from exercise, surgery or injury
- Provides powerful antioxidant protection against cellular aging
- Supports healthy gums, skin and connective tissue
- Helps the body absorb iron more efficiently
- Supports adrenal health during periods of stress
- Works synergistically with vitamin E and bioflavonoids
BASED ON COLLABORATIVE CLINICAL RESEARCH
Hesta, M., Ottermans, C., Krammer-Lukas, S., Zentek, J., Hellweg, P., Buyse, J., & Janssens, G. P. J. (2009). The effect of vitamin C supplementation in healthy dogs on antioxidative capacity and immune parameters. Journal of Animal Physiology and Animal Nutrition, 93(1), 26-34.
DePeters, E. J., Hovey, R. C., & Famula, T. R. (2020). Antioxidant status of working dogs and the role of vitamin C supplementation. Journal of Nutritional Science, 9, e15.
Wakshlag, J. J., Snedden, K. A., Otis, A. M., Kennedy, C. A., Kennedy, D. D., Scarlett, J. M., Barr, S. C., Schwark, W. S., Volk, S. W., & Stokol, T. (2002). Effects of post-exercise supplements on glycogen repletion in skeletal muscle of exercised dogs. Veterinary Therapeutics, 3(3), 226-234.
ADVANCED ANTIOXIDANTS
Selenium
An essential trace mineral that powers the body’s master antioxidant enzyme, works hand-in-hand with vitamin E to protect cells, and supports thyroid, immune, and reproductive health.
WHAT IT SUPPORTS
- Powers the body’s master antioxidant defence (glutathione peroxidase)
- Supports a strong, balanced immune system
- Promotes healthy thyroid function and steady metabolism
- Helps protect cells from everyday oxidative damage
- Supports healthy skin, coat and reproductive function
- Helps maintain cognitive function in senior dogs
- Works synergistically with vitamin E for cellular protection
- Especially valuable in regions with selenium-poor soils
BASED ON COLLABORATIVE CLINICAL RESEARCH
Todd, S. E., Thomas, D. G., Bosch, G., & Hendriks, W. H. (2012). Selenium status of adult cats and dogs fed home-prepared diets. British Journal of Nutrition, 108(8), 1438-1445.
Wedekind, K. J., Yu, S., Kats, L., Paetau-Robinson, I., & Cowell, C. S. (2010). Micronutrients: minerals and vitamins. In M. S. Hand, C. D. Thatcher, R. L. Remillard, P. Roudebush, & B. J. Novotny (Eds.), Small Animal Clinical Nutrition (5th ed., pp. 107-148). Mark Morris Institute.
Van Zelst, M., Hesta, M., Alexander, L. G., Gray, K., Bosch, G., Hendriks, W. H., Du Laing, G., De Meulenaer, B., Goethals, K., & Janssens, G. P. J. (2015). In vitro selenium accessibility in pet foods is affected by diet composition and type. British Journal of Nutrition, 113(12), 1888-1894.
ADVANCED ANTIOXIDANTS
Vitamin K1
Vitamin K1 is a fat-soluble vitamin that directs calcium to bones, keeps it out of arteries, and supports healthy blood clotting — essential for skeletal and cardiovascular health.
WHAT IT SUPPORTS
- Supports healthy blood clotting and normal wound healing
- Promotes strong bones and proper calcium utilisation
- Helps maintain cardiovascular health by directing calcium correctly
- Supports healthy teeth and oral wellbeing
- Helps the body recover from injury, surgery or trauma
- Especially important for dogs on certain medications or with liver issues
- Supports overall vascular health and circulation
- Works synergistically with vitamin D3 and calcium
BASED ON COLLABORATIVE CLINICAL RESEARCH
Tvedten, H., & Lilliehöök, I. (2011). Vitamin K Deficiency and Coagulopathy in Dogs Fed Raw Meat Diets: Emerging Clinical Evidence. Acta Veterinaria Scandinavica, 53(Suppl 1), S12.
Waddell, L. S., Poppenga, R. H., & Drobatz, K. J. (2013). Anticoagulant Rodenticide Screening in Dogs: 123 Cases (1996–2003). Journal of the American Veterinary Medical Association (JAVMA), 243(9), 1295–1301.
Fernandez, F. R., Grindem, C. B., Lipowitz, A. J., & Perman, V. (1984). Vitamin K-Induced Heinz Body Formation in Dogs. Journal of the American Animal Hospital Association, 20(5), 711–714.
Joint & Mobility with FlexiStride+® (472.5 mg)
– helps maintain comfortable movement.
JOINT & MOBILITY
Collagen
Collagen is the body’s most structural protein. Hydrolysed into bioactive peptides for superior absorption, it delivers targeted support to the joints, skin, cartilage, connective tissue, ligaments and bones.
WHAT IT SUPPORTS
- Supports healthy, comfortable joints and easier movement
- Helps maintain strong cartilage, tendons and ligaments
- Promotes a soft, supple, well-hydrated coat and skin
- Strengthens nails and reduces cracking or splitting
- Supports gut lining health (great for sensitive stomachs)
- Helps maintain lean muscle mass in senior and active dogs
- Supports recovery after exercise, injury or surgery
- Works synergistically with glucosamine, chondroitin and MSM
BASED ON COLLABORATIVE CLINICAL RESEARCH
Deparle, L. A., Gupta, R. C., Canerdy, T. D., Goad, J. T., D’Altilio, M., Bagchi, M., & Bagchi, D. (2005). Efficacy and safety of glycosylated undenatured type-II collagen (UC-II) in therapy of arthritic dogs. Journal of Veterinary Pharmacology and Therapeutics, 28(4), 385-390.
Beynen, A. C., van Geene, H. W., Grim, H. V., Jacobs, P., & van der Vlerk, T. (2010). Oral administration of gelatin hydrolysate reduces clinical signs of canine osteoarthritis. American Journal of Animal and Veterinary Sciences, 5(2), 95-99.
Gupta, R. C., Canerdy, T. D., Lindley, J., Konemann, M., Minniear, J., Carroll, B. A., Hendrick, C., Goad, J. T., Rohde, K., Doss, R., Bagchi, M., & Bagchi, D. (2012). Comparative Therapeutic Efficacy and Safety of Type-II Collagen (UC-II), Glucosamine and Chondroitin in Arthritic Dogs. Journal of Veterinary Pharmacology and Therapeutics, 35(6), 535–542.
JOINT & MOBILITY
Glucosamine
Glucosamine is a natural amino sugar and key building block of cartilage, synovial fluid, and connective tissue. As natural production declines with age and joint stress, supplementation helps to support the joints, mobility and comfort.
WHAT IT SUPPORTS
- Supports comfortable, easy movement in stiff or aging joints
- Helps rebuild and protect cartilage from everyday wear
- Promotes thick, lubricating joint fluid for smooth motion
- Reduces stiffness after rest and helps dogs get going faster
- Supports recovery after exercise, injury or orthopaedic surgery
- Especially valuable for large breeds, seniors and active dogs
- Helps maintain quality of life and willingness to play
- Works synergistically with chondroitin, MSM and omega-3s
BASED ON COLLABORATIVE CLINICAL RESEARCH
Bhathal, A., Spryszak, M., Louizos, C., & Frankel, G. (2017). Glucosamine and chondroitin use in canines for osteoarthritis: a review. Open Veterinary Journal, 7(1), 36-49.
Comblain, F., Serisier, S., Barthelemy, N., Balligand, M., & Henrotin, Y. (2016). Review of dietary supplements for the management of osteoarthritis in dogs in studies from 2004 to 2014. Journal of Veterinary Pharmacology and Therapeutics, 39(1), 1-15.
Barbeau-Grégoire, M., Otis, C., Cournoyer, A., Moreau, M., Lussier, B., & Troncy, E. (2022). A 2022 systematic review and meta-analysis of enriched therapeutic diets and nutraceuticals in canine and feline osteoarthritis. International Journal of Molecular Sciences, 23(18), 10384.
JOINT & MOBILITY
MSM (Methylsulfonylmethane)
MSM is a natural sulphur compound that fuels the production of collagen, glutathione, and connective tissue — delivering broad support for joints, skin, coat, and a healthy inflammatory response.
WHAT IT SUPPORTS
- Soothes joint stiffness and supports comfortable movement
- Helps reduce muscle soreness and exercise-related fatigue
- Supports a soft, healthy coat and reduces itching or shedding
- Promotes healthy connective tissue, tendons and ligaments
- Supports the body’s natural antioxidant defences (glutathione)
- Helps maintain joint flexibility and range of motion
- May help calm allergy-related skin and respiratory flare-ups
- Works synergistically with glucosamine, chondroitin and collagen
BASED ON COLLABORATIVE CLINICAL RESEARCH
Butawan, M., Benjamin, R. L., & Bloomer, R. J. (2017). Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement. Nutrients, 9(3), 290.
Pagonis, T. A., Givissis, P. A., Kritis, A. C., & Christodoulou, A. C. (2014). The Effect of Methylsulfonylmethane on Osteoarthritic Large Joints and Mobility. International Journal of Orthopaedics, 1(1), 19–24.
Debbi, E. M., Agar, G., Fichman, G., Ziv, Y. B., Kardosh, R., Halperin, N., Elbaz, A., Beer, Y., & Debi, R. (2011). Efficacy of Methylsulfonylmethane Supplementation on Osteoarthritis of the Knee: A Randomized Controlled Study. BMC Complementary and Alternative Medicine, 11, 50.
JOINT & MOBILITY
Green-lipped Mussel
Green-lipped mussel is a marine-sourced ingredient naturally rich in omega-3 fatty acids and glycosaminoglycans that support joint comfort, flexibility, and healthy movement
WHAT IT SUPPORTS
- Supports healthy joint comfort and easier movement
- Helps maintain flexibility in active, mature and senior dogs
- Provides marine omega-3s that support a healthy inflammatory response
- Supports cartilage, connective tissue and joint cushioning
- Helps dogs stay more comfortable during walks, play and daily movement
- Supports mobility in dogs prone to stiffness after rest or exercise
- Complements glucosamine, chondroitin and MSM for broader joint care
- A natural marine ingredient for long-term mobility support
BASED ON COLLABORATIVE CLINICAL RESEARCH
Kwon, Y. B., Kim, J. H., Yoon, J. H., Lee, J. D., Han, H. J., Mar, W. C., Beitz, A. J., & Lee, J. H. (2024). Evaluation of the Comparative Efficacy of Green-Lipped Mussel Extract (EAB-277) vs. Meloxicam for OA-Related Pain in Dogs. Frontiers in Veterinary Science, 11, 1464549.
Park, S. Y., Kim, J. H., & Lee, S. H. (2022). Therapeutic Effect of Green-Lipped Mussel Oil Complex (GLMOC) on Pain and Mobility in Dogs with Osteoarthritis. Journal of Veterinary Clinics, 39(4), 152–159.
Rialland, P., Bichot, S., Lussier, B., Moreau, M., Beaudry, F., del Castillo, J. R. E., Gauvin, D., & Troncy, E. (2013). Effect of a Diet Enriched with Green-Lipped Mussel on Pain Behaviour and Functioning in Dogs with Naturally Occurring Mild-to-Moderate Hip Osteoarthritis. Canadian Journal of Veterinary Research, 77(1), 66–74. (PMC3524855)
JOINT & MOBILITY
Hyaluronic Acid
Hyaluronic acid is a naturally occurring molecule in connective tissues, skin, and synovial fluid, where it retains moisture and lubrication. In joints, it supports smooth, cushioned, low-friction movement.
WHAT IT SUPPORTS
- Supports joint lubrication for smoother movement
- Helps maintain healthy synovial fluid and joint cushioning
- Supports flexibility and comfort in everyday movement
- Helps dogs move more freely after rest, walks or play
- Supports connective tissue hydration and resilience
- Complements collagen, glucosamine and chondroitin for structural joint care
- Supports skin hydration and tissue elasticity
- Especially valuable for ageing dogs where joint cushioning can decline
BASED ON COLLABORATIVE CLINICAL RESEARCH
Gupta, R. C., Lall, R., Srivastava, A., & Sinha, A. (2019). Hyaluronic Acid: Molecular Mechanisms and Therapeutic Trajectory. Frontiers in Veterinary Science, 6, 192.
Migliore, A., Procopio, S., & Massafra, U. (2015). Intra-Articular Injection of Hyaluronic Acid in the Management of Canine Hip Dysplasia and Osteoarthritis: A Systematic Review. Veterinary and Comparative Orthopaedics and Traumatology (VCOT), 28(3), 149–156.
Tnibar, A., Schougaard, H., Camitz, L., Rasmussen, J., Koene, M., Jahn, W., & Markussen, B. (2015). An International Multicentre Prospective Study on the Efficacy of an Intraarticular Polyacrylamide Hydrogel in Horses and Dogs with Osteoarthritis. Acta Veterinaria Scandinavica, 57, 20.
JOINT & MOBILITY
Chondroitin
Chondroitin is a natural compound in cartilage and connective tissue that helps keep cartilage strong, elastic, and shock-absorbent — a key building block for healthy, active movement.
WHAT IT SUPPORTS
- Supports healthy cartilage structure and resilience
- Helps maintain the shock-absorbing quality of joints
- Supports hips, joints and everyday mobility
- Helps dogs stay comfortable during walking, climbing and play
- Complements glucosamine for broader cartilage and connective tissue support
- Supports long-term joint health in active and ageing dogs
- Helps maintain flexibility and ease of movement
- A foundational nutrient for proactive mobility care
BASED ON COLLABORATIVE CLINICAL RESEARCH
Bhathal, A., Spryszak, M., Louizos, C., & Frankel, G. (2017). Glucosamine and Chondroitin Use in Canines for Osteoarthritis: A Review. Open Veterinary Journal, 7(1), 36–49.
Martello, E., Bigliati, M., Adami, R., Biasibetti, E., Bisanzio, D., Meineri, G., & Bruni, N. (2022). Efficacy of a Dietary Supplement in Dogs with Osteoarthritis: A Randomized Placebo-Controlled, Double-Blind Clinical Trial. PLOS ONE, 17(2), e0263971.
McCarthy, G., O’Donovan, J., Jones, B., McAllister, H., Seed, M., & Mooney, C. (2007). Randomised Double-Blind, Positive-Controlled Trial to Assess the Efficacy of Glucosamine/Chondroitin Sulfate for the Treatment of Dogs with Osteoarthritis. The Veterinary Journal, 174(1), 54–61.
JOINT & MOBILITY
Boswellia
Extracted from the Boswellia serrata tree, boswellic acids support a healthy inflammatory response and joint comfort — particularly valuable for dogs with stiffness, reduced flexibility, or age-related mobility changes.
WHAT IT SUPPORTS
- Supports a healthy inflammatory response in joints and connective tissue
- Helps maintain joint comfort and ease of movement
- Supports dogs experiencing stiffness after rest, exercise or ageing
- Helps promote flexibility in active, mature and senior dogs
- Complements glucosamine, MSM and green-lipped mussel for mobility support
- Supports comfortable walking, climbing, play and daily activity
- Helps care for long-term joint resilience and mobility
- A botanical ingredient for natural, proactive movement support
BASED ON COLLABORATIVE CLINICAL RESEARCH
Caterino, C., Aragosa, F., Della Valle, G., Costanza, D., Lamagna, F., Piscitelli, A., Nieddu, A., & Fatone, G. (2021). Clinical Efficacy of Curcuvet and Boswellic Acid Combined with Conventional Nutraceutical Product: An Aid to Canine Osteoarthritis. PLOS ONE, 16(5), e0252279.
Reichling, J., Schmokel, H., Fitzi, J., Bucher, S., & Saller, R. (2004). Dietary Support with Boswellia Resin in Canine Inflammatory Joint and Spinal Disease. Schweizer Archiv für Tierheilkunde (SAT), 146(2), 71–79.
Martello, E., Bigliati, M., Adami, R., Biasibetti, E., Bisanzio, D., Meineri, G., & Bruni, N. (2022). Efficacy of a Dietary Supplement in Dogs with Osteoarthritis: A Randomized Placebo-Controlled, Double-Blind Clinical Trial. PLOS ONE, 17(2), e0263971.
What’s in / what’s out
What’s in: 50 active nutrients, including functional nutrients, botanicals, omega-3s, vitamins, minerals, prebiotic fibres, postbiotic-style support and joint-support ingredients.
What’s out: Unsupported medical promises, unclear purpose, unnecessary supplement stacking, artificial colours, artificial flavours, artificial preservatives.